radiosensitizer

radiosensitizer

 [ra″de-o-sen´sĭ-ti″zer]
a chemotherapeutic agent used to enhance the effect of radiation therapy.

ra·di·o·sen·si·tiz·er

(rā'dē-ō-sen'si-tīz'ĕr),
A chemical substance that increases the radiosensitivity of tissues; restoring normal tissue oxygen tension to an anoxic region is also an effective radiosensitizer.

radiosensitizer

Oncology A drug that ↑ tumor cell sensitivity to radiation. See Radiosensitization.
References in periodicals archive ?
Temozolomide is the routinely used radiosensitizer during radiotherapy and chemotherapy cycles and has shown good results.
Luteolin acts as a radiosensitizer in nonsmall cell lung cancer cells by enhancing apoptotic cell death through activation of a p38/ROS/caspase cascade.
Curcumin, the golden spice from Indian saffron, is a chemosensitizer and radiosensitizer for tumors and chemoprotector and radioprotector for normal organs.
com)-- Tucson based pharmaceutical company NuvOx Pharma announced today that it has secured orphan drug designation from the FDA for its investigational radiosensitizer for glioblastoma multiforme.
Oxygen free radicals are highly reactive and are the primary source of radiation-induced DNA damage, and oxygen is, therefore, a potent radiosensitizer.
Chemotherapy has been thought to be an effective radiosensitizer, inducing more cellular damage, more fibrosis, and obliteration of the microcirculation [33].
Chemotherapy acts as a radiosensitizer, and it helps decrease the rate of distant metastasis.
Related preclinical studies using Provecta(TM) as a radiosensitizer currently are underway at the University of Wisconsin-Madison.
Beta-carotene is being studied, both as a radiosensitizer and as a radioprotector (a substance that protects normal cells from radiation damage).
NCT01088035 ("Carboplatin as a Radiosensitizer in Treating Childhood Ependymoma")