Temozolomide is the routinely used radiosensitizer
during radiotherapy and chemotherapy cycles and has shown good results.
Luteolin acts as a radiosensitizer
in nonsmall cell lung cancer cells by enhancing apoptotic cell death through activation of a p38/ROS/caspase cascade.
Curcumin, the golden spice from Indian saffron, is a chemosensitizer and radiosensitizer
for tumors and chemoprotector and radioprotector for normal organs.
com)-- Tucson based pharmaceutical company NuvOx Pharma announced today that it has secured orphan drug designation from the FDA for its investigational radiosensitizer
for glioblastoma multiforme.
Oxygen free radicals are highly reactive and are the primary source of radiation-induced DNA damage, and oxygen is, therefore, a potent radiosensitizer
Chemotherapy has been thought to be an effective radiosensitizer
, inducing more cellular damage, more fibrosis, and obliteration of the microcirculation .
Gemcitabine as a radiosensitizer
for nonresectable cat oral squamous cell carcinoma.
Whole brain radiotherapy with radiosensitizer
for brain metastases.
Chemotherapy acts as a radiosensitizer
, and it helps decrease the rate of distant metastasis.
Related preclinical studies using Provecta(TM) as a radiosensitizer
currently are underway at the University of Wisconsin-Madison.
Beta-carotene is being studied, both as a radiosensitizer
and as a radioprotector (a substance that protects normal cells from radiation damage).
NCT01088035 ("Carboplatin as a Radiosensitizer
in Treating Childhood Ependymoma")