radiosensitizer

radiosensitizer

 [ra″de-o-sen´sĭ-ti″zer]
a chemotherapeutic agent used to enhance the effect of radiation therapy.

ra·di·o·sen·si·tiz·er

(rā'dē-ō-sen'si-tīz'ĕr),
A chemical substance that increases the radiosensitivity of tissues; restoring normal tissue oxygen tension to an anoxic region is also an effective radiosensitizer.

radiosensitizer

Oncology A drug that ↑ tumor cell sensitivity to radiation. See Radiosensitization.
References in periodicals archive ?
com)-- Tucson based pharmaceutical company NuvOx Pharma announced today that it has secured orphan drug designation from the FDA for its investigational radiosensitizer for glioblastoma multiforme.
Curcumin: a new radiosensitizer of squamous cell carcinoma cells.
Of special interests, curcumin acts as a chemosensitizer and radiosensitizer for tumors while chemoprotector and radioprotector for normal organs (Goel and Aggarwal 2010).
Chemotherapy acts as a radiosensitizer, and it helps decrease the rate of distant metastasis.
Related preclinical studies using Provecta(TM) as a radiosensitizer currently are underway at the University of Wisconsin-Madison.
NCT01088035 ("Carboplatin as a Radiosensitizer in Treating Childhood Ependymoma")
Research has also shown that VAL-083 is highly effective against GBM cancer stem cells (CSC) and non-CSC and acts as a radiosensitizer in GBM cell lines, in vitro.
It is stated that Nimoral is a hypoxic radiosensitizer to enhance the effect of radiotherapy in head and neck cancer patients.
Background & objectives: Temozolomide (TMZ), a second generation alkylating drug, an effective cytotoxic agent as well as radiosensitizer for malignant brain tumours, has side effects like myelosuppression.