Mechanism of radiosensitization
by halogenated pyrimidines: effects of BrdU on radiation induction of DNA and chromosome damage and its correlation with cell killing.
Many recent studies have reported the beneficial effects of TET on tumor cell cytotoxicity and radiosensitization
, multidrug resistance, promotion of apoptosis, normal tissue radioprotection, and angiogenesis (Chen 2002).
Focuses of the review are the biological rationales of hyperthermia in regard to direct cytotoxicity, systemic effects, chemosensitization, radiosensitization
, and immune modulation.
These experiments may identify a new therapeutic regimen for prostate cancer and identify candidate genes for statin-mediated radiosensitization
There are several radiobiological rationales that may explain our observation including radiosensitization
by the rose bengal, additive cell kill or augmentation of the host immune response by the interaction of the two modalities.
in viral gene therapy (Jula Veerapong, Kai A.
Study results showed that Tarceva(TM), when utilized in combination with radiation, contributes to an increase in radiosensitization
(sensitivity of tissue to the effects of radiation therapy).
Michael Pollak of McGill University were designed to further examine the radiosensitization
properties of rhIGFBP-3 in vitro and to evaluate the inhibitory effects of rhIGFBP-3 administration on tumor growth in vivo.
6,051,218 entitled, "Tumor Radiosensitization
Using Gene Therapy.
Session: HDAC Inhibitors 1 Poster Presentation: Radiosensitization
by the HDAC inhibitor PCI-24781 in SiHa and WiDr human tumor cell lines Abstract #695: 8:00 a.
5,478,806, "Enhancement of Anti-Tumor Therapy with Hemoglobin-Based Conjugates", covers tumor radiosensitization
with PEG-hemoglobin, regardless of source of hemoglobin or type of PEG conjugate.
The Company received its fourth pharmaceutical patent covering the use of the Company's anti-cancer pharmaceutical agent PV-10 for radiosensitization
, augmenting coverage provided by the Company's earlier patents for cancer treatment and diagnostic imaging using CT, MRI and ultrasound.