radioresistance


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radioresistance

 [ra″de-o-re″zis´tans]
resisting the effects of radiation, especially in reference to the treatment of malignancy. adj., adj radioresist´ant.

radioresistance

/ra·dio·re·sis·tance/ (-re-zis´tins) resistance, as of tissue or cells, to irradiation.radioresist´ant

radioresistance

[-risis′təns]
Etymology: L, radiare + resistare, to withstand
the ability of cells, tissues, organs, organisms, chemical compounds, or any other substances to remain unchanged by radiation. Compare radiosensitivity. radioresistant, adj.

radioresistance

Radiation oncology The relative resistance of cells and tissues to irreversible damage by radiation; RR is greatest in terminally differentiated tissues–eg, bone, cartilage, muscle, peripheral nerve, and in certain tumors–eg, glioma, melanoma, renal cell carcinoma, sarcoma. Cf Radiosensitivity.

radioresistance (rā´dēōrēzis´təns),

n the relative resistance of cells, tissues, organs, or organisms to the injurious effects of ionizing radiation. See also radiosensitivity.

radioresistance

resisting the effects of radiation, especially in reference to the treatment of malignancy.
References in periodicals archive ?
A fuller understanding of the biological basis of radioresistance in breast cancer is needed to underpin the rationale design of therapeutic strategies to overcome it.
They concluded that hyperthermia acts as "a radiosensitizer in the treatment of hypodense (at CT scan) metastatic nodes overcoming the radioresistance of necrotic, presumably hypoxic nodal metastases.
Proposal Title: Defining the role of AR Signaling in Promoting Prostate Cancer Radioresistance
Targeting transcription factor NF-kappa B to overcome chemoresistance and radioresistance in cancer therapy.
Epidermal growth factor receptor in glioma: signal transduction, neuropathology, imaging, and radioresistance.
A specific checkpoint kinase inhibitor reversed this radioresistance and repaired radiation-induced DNA damage more effectively than CD[133.
Hypersensitivity to very low single radiation doses: its relationship to the adaptive response and induced radioresistance.
In clinical situation cancer patients need radiotherapy, radioprotector may aid in reducing radiation toxicity of normal tissues without increasing tumor radioresistance.
Genotoxic effects, its modulation by polyvitamin treatment and evaluation of the induced radioresistance.
Loss of PTEN functioning results in unregulated PI3K/Akt/mTOR pathway activation, promoting cellular proliferation, migration, and radioresistance.
A cause of radioresistance in retinoblastoma: photoreceptor differentiation.
In short, they will produce or enhance the constitutive activation of the NF-[kappa]B pathway, potentially leading to more chemo-resistance or radioresistance.