Curcumin, the golden spice from Indian saffron, is a chemosensitizer and radiosensitizer for tumors and chemoprotector and radioprotector
for normal organs.
With new technology we have three main areas of focus - hyperthermia, radioprotector
and hollow microspheres.
in locally advanced head and neck tumors.
Movsas was the principal investigator of the largest national randomized study of a radioprotector
, called amifostine, to reduce radiation injury in lung cancer patients.
Studies on the aqueous extract of Terminalia chebula as a potent antioxidant and a probable radioprotector
Resveratrol is both a radioprotector
in healthy tissue and also has anti-tumor activity.
Our first radioprotector
is in late stage development for use in defense and anti-terrorism applications.
Of special interests, curcumin acts as a chemosensitizer and radiosensitizer for tumors while chemoprotector and radioprotector
for normal organs (Goel and Aggarwal 2010).
We believe that these remarkable results demonstrate the potential of CBLB502 as a powerful radioprotector
and represent a significant step towards FDA approval of our radiation antidote candidate for military and civil defense applications," said Michael Fonstein, CEO and President of CBL.
Evidences show that IR has potentials to be a radioprotector
, especially in recovery of hematopoietic system, reduction of inflammatory cytokines and intestinal toxicity.
Appropriate negative and positive control groups (treated with chemical radioprotector
AET) were also selected and handled in the same manner.
The article, "Phase III Randomized Trial of Amifostine as a Radioprotector
in Head and Neck Cancer," details the expanded use of Ethyol in an important radiation setting, specifically, the reduction of moderate-to-severe xerostomia (dry mouth) which was approved by the U.