radiolabelled


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radiolabelled

adjective Referring to a molecule or substance that has been linked to a radioactive substance, which can be detected in vivo (e.g., radionuclide scan) or in vitro in a fluid (e.g., radioimmunoassay).
References in periodicals archive ?
Written for practitioners in nuclear medicine, this publication from the International Atomic Energy Agency provides guidance on the safe and effective use of radiolabelled monoclonal antibodies and peptides which bind to cell surface rectors and address aberrant cellular function or those overexpressed in certain diseases.
Jozsef Repasi, Managing Director of Ubichem Research commented: This approval enables us to supply radiolabelled materials for use in human clinical trials, and is a reflection of the skill and hard work of our dedicated team in Budapest, building on the approval obtained previously for the commercial supply of cGMP APIs.
Charles River's reputation is world-renowned for their conduct of studies using radiolabelled investigational products.
The amount of the radioactivity from the radiolabelled CIC-HFA and radiolabelled CIC-AQ remaining in the nasal cavity and lungs were measured to determine the nasal and pulmonary deposition.
Director of Business Development for Radiochemistry, Dave Roberts added: "By selecting Selcia for the preparation of their 14C GMP radiolabelled APIs, clients have the widest choice of phase 1 clinics for their human clinical trials.
Selcia's radiolabelling division produces C-14 radiolabelled compounds for a global customer base encompassing both the life sciences and chemical industries.
The OMP designation has been granted on the basis that: follicular lymphoma affects fewer than 5 in 10,000 persons in the European Community; the condition is serious and life-threatening; although satisfactory methods of treatment have been authorized in Europe, tositumomab and Iodine I 131 radiolabelled tositumomab may be of significant benefit to those affected by the condition.
Rats were fed a test meal of fat containing radiolabelled cholesterol.
This affinity, combined with NeoTect's radiolabelled technetium-99m, a safe and inexpensive radioisotope imaged through widely available gamma camera systems, allowed clinicians in the study to precisely distinguish the malignant versus the nonmalignant small tumors.
The study involved intravenous administration of a radiolabelled version of the antibody to patients with recurrent B-cell non-Hodgkin's' lymphoma (NHL) and was conducted at the B.
Measurable radiolabelled platinum was present in treated tumors 72 hours following administration compared to no detectable drug after two hours in the controls.
Concentrations of radiolabelled platinum in tumors treated with IntraDose-CDDP were markedly higher than in those injected with simple aqueous suspensions of equal doses of CDDP.