radiolabelled


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radiolabelled

adjective Referring to a molecule or substance that has been linked to a radioactive substance, which can be detected in vivo (e.g., radionuclide scan) or in vitro in a fluid (e.g., radioimmunoassay).
References in periodicals archive ?
Founded in 2003, Pharmaron has invested in its people and facilities, and established a broad spectrum of R/D service capabilities ranging from synthetic and medicinal chemistry, biology, DMPK, pharmacology, safety assessment, radiochemistry and radiolabelled metabolism to chemical and pharmaceutical development.
Written for practitioners in nuclear medicine, this publication from the International Atomic Energy Agency provides guidance on the safe and effective use of radiolabelled monoclonal antibodies and peptides which bind to cell surface rectors and address aberrant cellular function or those overexpressed in certain diseases.
Jozsef Repasi, Managing Director of Ubichem Research commented: This approval enables us to supply radiolabelled materials for use in human clinical trials, and is a reflection of the skill and hard work of our dedicated team in Budapest, building on the approval obtained previously for the commercial supply of cGMP APIs.
The amount of the radioactivity from the radiolabelled CIC-HFA and radiolabelled CIC-AQ remaining in the nasal cavity and lungs were measured to determine the nasal and pulmonary deposition.
QPS's reputation is world-renowned for their conduct of studies determining absorption, distribution, metabolism and excretion (ADME) patterns in laboratory animals (including those employing radiolabelled investigational products) and humans.
Director of Business Development for Radiochemistry, Dave Roberts added: "By selecting Selcia for the preparation of their 14C GMP radiolabelled APIs, clients have the widest choice of phase 1 clinics for their human clinical trials.
Charles River's reputation is world-renowned for their conduct of studies using radiolabelled investigational products.
Selcia's extended capability of now being able to produce GMP radiolabelled API material will shorten the timeframe for our clients to commence key Phase 1 clinical trials".
Selcia Radiolabelling is a proven leader in delivering pure radiolabelled compounds for preclinical and clinical ADME studies.
Greater than 95% of radiolabelled Occlusin(TM) Injection was retained in the target organ.
Animal studies (GLP): BA, BE, PK, ADME, tissue distribution of radiolabelled Drug Information Association Veterinary studies: MRL studies in farm animals.
This feature means that combining the new chelating agent with a biologically active molecule results in a compound that can be subsequently radiolabelled with an appropriate radioisotope to form a new diagnostic or therapeutic agent.