Also found in: Dictionary, Thesaurus, Encyclopedia.
Kidney damage due to injected contrast occurs most often in people who are dehydrated or have diabetes mellitus, heart failure, impaired renal blood flow or kidney disease, liver failure, or multiple myeloma. It sometimes results in serious illness and death, increased hospital length of stay, and end-stage renal disease. Health care professionals should acquire complete medical histories and baseline blood tests to identify at-risk patients. Aggressive preprocedure hydration with sodium bicarbonate in saline decreases the incidence of radiocontrast nephropathy (RCN) in at-risk patients. Maintaining a urine volume more than 150 mL/hr before, during, and after contrast-requiring procedures reduces the rate of RCN significantly.