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radiation sensitizer

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radiation sensitizer
Oncology Any agent which ↑ cell susceptibility to ionizing radiation Explanation Most CA cells are hypoxic and thus more resistant to radiation; a hypoxic-cell RS–eg, etanidazole, misonidazole, nimorazole would, theoretically, improve radiation killing of CA cells–results have been disappointing. See Radiation therapy.


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Allos Therapeutics expects to use the proceeds from the financing for the development of the company's lead investigational radiation sensitizer, RSR13 (efaproxiral), and for general working capital.
In this trial, patients with advanced pancreatic cancer with no prior chemotherapy except as a radiation sensitizer received escalating doses of nab-paclitaxel (ABRAXANE([R])) from 100 mg/m2 to 150 mg/m2 combined with 1000 mg/m2 of gemcitabine.
The study is the first to demonstrate the utility of GRN163L as a radiation sensitizer in cancer therapy.
 
 
 
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