rabeprazole


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Related to rabeprazole: Pantoprazole, rabeprazole sodium, Domperidone

rabeprazole

 [rah-bep´rah-zōl]
an inhibitor of stomach hydrochloric acid secretion administered orally as the sodium salt in treatment of gastroesophageal reflux disease and similar conditions marked by excessive acid.

rabeprazole

/ra·bep·ra·zole/ (rah-bep´rah-zōl) a proton pump inhibitor used as the sodium salt to inhibit gastric acid secretion in the treatment of gastroesophageal reflux disease and conditions marked by excessive secretion of gastric acid.

rabeprazole

a proton pump inhibitor.
indications Rabeprazole is used to treat gastroesophageal reflux disease (GERD), severe erosive esophagitis, poorly responsive systemic GERD, pathological hypersecretory conditions such as Zollinger-Ellison syndrome, systemic mastocytosis, multiple endocrine adenomas, and active duodenal ulcers.
contraindication Known hypersensitivity to this drug prohibits its use.
adverse effects Life-threatening effects are proteinuria, hematuria, pancytopenia, thrombocytopenia, neutropenia, and leukocytosis. Other adverse effects include abdominal swelling, anorexia, irritable colon, esophageal candidiasis, epistaxis, urticaria, alopecia, hypoglycemia, increased hepatic enzymes, weight gain, tinnitus, angina, tachycardia, bradycardia, palpitations, peripheral edema, urinary tract infection, increased creatinine, testicular pain, glycosuria, and fever. Common side effects include headache, dizziness, asthenia, diarrhea, abdominal pain, vomiting, nausea, constipation, flatulence, acid regurgitation, upper respiratory infections, cough, rash, and back pain.

rabeprazole

Aciphex® GI disease A proton pump inhibitor used to manage for heartburn, duodenal ulcers, gastric ulcers, GERD, hypersecretory conditions–eg, Zollinger-Ellison syndrome. See GERD.
References in periodicals archive ?
Horn J, Review article: relationship between the metabolism and efficacy of proton pump inhibitors - focus on rabeprazole.
Eisai's patent claims rabeprazole, the active ingredient in Aciphex[R], which is part of a class of drugs know as proton pump inhibitors, which suppress gastric acid production by inhibiting action of the enzyme H+K+ATPase.
Esomeprazole and omeprazole may interfere with the cytochrome system, whereas rabeprazole and pantoprazole have minimal significant drug interactions.
pylori are achieved by triple therapy consisting of a combination of two antibiotics [amoxicillin (AMC), clarithromycin (CAM), tinidazole (TNZ) and metronidazole (MNZ)] and one proton pump inhibitor (PPI) [omeprazole (OPZ), lansoprazole (LPZ), pantoprazole (PPZ) or rabeprazole (RPZ)].
However, the researchers concede that further studies are required to determine whether newer, less widely used PPIs-such as rabeprazole (Aciphex) and dexlansoprazole (Kapidex)-are also associated with increased cardiovascular risk in patients taking clopidogrel.
Her medications were carvedilo1 25 mg twice daily, pravastatin 10 mg nocte, rabeprazole 20 mg daily, aspirin 100 mg daily, perindopril 4 mg daily and frusemide 40 mg mane.
His medications at the time of his fire ant exposure included the following: fexofenadine, antipyrene/benzocaine, ammonium lactate, naproxen, terazosin, simvastatin, sodium levothyroxine, aspirin, gemfibrozil, rabeprazole sodium, diltiazem, and nitroglycerin.
proton pump inhibitors, such as esomeprazole, lansoprazole, omeprazole, pantoprazole, rabeprazole
Contract awarded for 2588 order code 10580 rabeprazole sodium enteric coated tablet with 20 mg
The results of the study showed a statistically significant reduction in the cumulative incidence of recurrent gastric or duodenal ulcer among the patient groups administered 5 mg and 10 mg of rabeprazole, respectively, when compared to a comparator, thereby demonstrating the superiority of rabeprazole in preventing ulcer recurrence.