A class of alkaloids based on the quinolizidine (norlupinane) structure.
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Kinghorn and Smolenski (1981) comment that the occurrence of such complex quinolizidines is noteworthy because Acosmium is considered one of the primitive genera of the tribe Sophoreae.
The lycopodium alkaloid huperzine A [9] related to the quinolizidines, is a potent, yet reversible, inhibitor of AChE and is used in China for treating patients with myasthenia gravis and AD.