quinoline


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quinoline

 [kwin´o-lēn]
an amine or alkaloid derivable from quinine, coal tar, and various other sources, which has antiseptic, antipyretic, and antimalarial properties.

quin·o·line

(kwin'ō-lēn, -lin),
1. A volatile nitrogenous base obtained by the distillation of coal tar, bones, alkaloids, and other substances; a basic structure of many dyes and drugs; also used as an antimalarial. Synonym(s): chinoleine, leucoline
2. One of a class of alkaloids based on the quinoline (1) structure.

quinoline

(kwĭn′ə-lēn′, -lĭn)
n.
An aromatic organic base, C9H7N, having a pungent tarlike odor, synthesized or obtained from coal tar, and used as a food preservative and in making antiseptics, drugs, and dyes.

quinoline

[kwin′o-lēn]
an amine or alkaloid; with antiseptic, antipyretic, and antimalarial properties, derivable from quinine, coal tar, and various other sources.

quinoline

a drug used originally as an antimalarial. Some of its derivatives are used as antiprotozoal and topical antifungal agents, e.g. quinuronium sulfate, 4-aminoquinoline, di-iodohydroxyquinoline and clioquinol (iodochlorhydroxyquin).
References in periodicals archive ?
The same result was observed for quinolines, an antifolate, or atovaquone (Table 1).
In semi-Bayes models with multiple pollutants as predictors, designed to determine which among many correlated pollutants were associated with ASD, associations with styrene and quinoline just reached significance (Kalkbrenner et al.
Reaction of 1 with ethyl cyanoacetate in the presence of catalytic amount of piperidine furnished the chromene derivative (12), while its reaction with ethyl cyanoacetate in the presence of ammonium acetate gave the quinoline derivative (13).
1952, "Treatment of experimental tuberculosis in guinea pig by iodochloroxy quinoline, "Ann.
It has been shown that electron transfer fluorescence quenching does take place in quinoline betaines compounds.
8) DHPPA, a different isomer, has been claimed to be a metabolite of Pseudomonas species, but the literature indicates that this compound is formed by the in vitro action of these species on quinoline, a component of coal tar -a substance missing from the diet of virtually all humans.
The regulation requires that synthetic azo dyes, otherwise known as the 'Southampton Six': sunset yellow (E110), quinoline yellow (E104), carmoisine (E122), allura red (E129), tartrazine (E102), and Ponceau 4R (E124) be labelled by their common names or E numbers in the list of ingredients along with the following warning statement: "may have an adverse effect on activity and attention in children".
The Southampton 6 additives u Tartrazine (E102), Quinoline Yellow (E104), Sunset Yellow (E110), Carmoisine (E122), Ponceau Red (E124), Allura Red (E129) u have been found to cause serious health and behavioural problems in children.
Quinoline antimalarials mechanisms of action & prospects for new agents.
Colourants such as sunset yellow, tartrazine and quinoline yellow were linked to hyperactivity in children by Southampton University two years ago, prompting the EU to introduce warning labels.
These quinoline derivatives can cause similar reversible myopathies, although the chloroquine myopathy is generally more severe.
X-ray crystallographic analysis revealed zinc coordinated to an oxygen atom from each of two sulphate bridges, a chlorine atom and quinoline atom ([N.