quinagolide

quinagolide

A drug with properties similar to those of DOPAMINE used to treat infertility in women with excess levels of the hormone prolactin. A brand name is Norprolac.
References in periodicals archive ?
Among currently available dopamine agonists, cabergoline, quinagolide and bromocriptine are the most common drugs that should be used for prevention of both early and late OHSS.
Quinagolide used in a fixed regimen of three oral doses (50,100 and 200 [micro]g/day), starting on the day of hCG and continued for 17-21 days, significantly reduces the frequency of moderate/severe early OHSS (12% vs.
Among dopamine agonists used, cabergoline, quinagolide and bromocriptine are the most common drugs that should be considered for OHSS prevention, especially for moderate forms of the syndrome, without adverse effects on pregnancy outcome.
Dopamine agonists like bromocriptine, cabergoline and quinagolide administration restores normal ovarian function and is the first line treatment for most patients wishing to conceive.
It has been reported that treatment of prolactinoma with dopamine 2 receptor agonists such as bromocriptine, lisuride, cabergoline, and quinagolide may provoke the disease [9].
Hormone levels and tumour size response to quinagolide and cabergoline in patients with prolactin-secreting and clinically non-functioning pituitary adenomas: predictive value of pituitary scintigraphy with 123I-methoxybenzamide.
Additionally, some studies emphasize the effects of bromocriptine, cabergoline, and quinagolide therapies in the treatment of FSHoma (16).
La administracion de agonistas dopaminergicos como la bromocriptina, caber goline, quinagolide, metergoline y lisuride inhiben la produccion de prolactina causando una disminucion del volumen celular individual y subsecuentemente inducen la reduccion tumoral; la normalizacion de los niveles de prolactina con el uso de la terapia dopaminergica ha sido reportada en un 70-90% y el decrecimiento tumoral en un 80-90%12.
Several dopamine agonists are currently available for the treatment of hyperprolactinemia, including bromocriptine and cabergoline in the USA and, additionally, quinagolide in the UK and most other European countries (2,4).
Other drugs used for treatment of prolactinomas that have not been approved by the FDA include mesylate, lisuride and quinagolide (Shimon & Melmed, 1998).
Quinagolide (D(2/3) agonist), ropinirole (D(2/3/4) agonist), SKF 38393 (D(1/5) agonist), AR-C68397AA (Viozan) (dual D(2)/B(2) agonist) and dopamine all inhibit hypertonic saline induced depolarization by approximately 50% (14).
Medical Treatment: The current gold standard medical treatment of Hyperprolactinemia is with dopamine agonist drugs, such as bromocriptine, Cabergoline and quinagolide.