quinacrine


Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.
Related to quinacrine: mepacrine

quinacrine

 [kwin´ah-krin]
an anthelmintic and antiprotozoal agent used especially for treatment of malaria, giardiasis, and tapeworm infestations. It is a yellow fluorescent dye also used in chromosome banding.

quinacrine

/quin·a·crine/ (kwin´ah-krin) an antimalarial, antiprotozoal, and anthelmintic, used as the hydrochloride salt, especially for suppressive therapy of malaria and in the treatment of giardiasis and tapeworm infestations.

quinacrine

(kwĭn′ə-krēn′)
n.
A compound, C23H30ClN3O, administered in its hydrochloride form, that was formerly used as an antimalarial and antihelminthic drug and, in some countries, has been used as an agent for the nonsurgical sterilization of women.

quinacrine

Classic cytogenetics A fluorescent dye used to stain chromosomes, especially Y chromosome Gynecology Tropical medicine An antiparasitic agent once used to manage giardiasis, helminths, malaria, protozoa, tapeworms

quinacrine

A yellow acridine dye useful in studying chromosomal structure because of its property of fluorescing when bound to certain regions of chromosomes. Also known as mepacrine. Quinacrine was once widely used to prevent malaria and to remove tapeworms.

quinacrine (kwin´əkrēn, -krin),

n an anthelmintic and antiprotozoal agent used to treat giardiasis and tapeworm infections. It is not effective in treating malaria.

quinacrine

an antimalarial, antiprotozoal and anthelmintic used especially for suppressive therapy of malaria in humans and also in the treatment of giardiasis in dogs. Called also mepacrine.
References in periodicals archive ?
At this point the UCSF researchers are still recruiting patients to help them determine if quinacrine helps, does nothing, or even worsens human prion diseases, Dr.
Preliminary animal studies suggest that the antibiotic erythromycin may be more effective than quinacrine for nonsurgical female sterilization.
The doctors said clinical tests on the use of the drug quinacrine -- the first of its kind in Japan -- showed it prevented the condition of four CJD patients in Fukuoka, Tochigi and Nara prefectures from worsening, although the condition of two of them later deteriorated a little.
Ms Forber was taken to San Francisco for treatment and placed on a course of quinacrine.
Her dad, Stephen, 42, scoured the Internet in a bid to find help and her condition improved dramatically after she was put on quinacrine by doctors in San Francisco.
In August, Prof Prusiner invited Rachel to his clinic in San Francisco, California, to be the first human to undergo a course of the drug Quinacrine.
Rachel was taken to San Francisco for treatment and placed on a course of quinacrine.
Tatsuo Yamada, a professor at Fukuoka University's School of Medicine, heads the medical team which will first orally give the man quinacrine, an anti-malaria drug, three times a day in 100 milligram doses.
The move comes after a US team investigating quinacrine came up with remarkable results on a Briton with the human form of "mad cow" disease.
Until a recent Supreme Court decision banning its use, the drug quinacrine had been used to sterilise women despite a World Health Organization warning about side effects.
Quinacrine is an extremely problematic drug that was developed in the 1920s as a malaria treatment and was never approved by the FDA for use as a contraceptive.
Specific antimalarials used to treat lupus include hydrochloroquine (Plaquenil), chloroquine (Aralen), and quinacrine (Atabrine).