quadrupole mass filter


Also found in: Acronyms.

quadrupole mass filter

a four-pole magnet system used to separate charged mass fragments in a mass spectrometer.

quadrupole mass filter

A term of art used in mass spectrometry for a specific combination of direct current (DC) and radiofrequency (RF) voltages which, when applied to four parallel metal rods, creates a filtering device that limits the transmission of ions to a certain defined m/z value. Changing the ratio of the voltages changes the m/z value of ions that pass through to the detector. The quadrupole mass filter can also be operated in other modes, such as passing a mass range of ions to the detector. If only the RF portion of the voltage is applied to the rods, virtually all ions pass to the detector.
References in periodicals archive ?
This unit is equipped with a quadrupole mass filter coupled with a high resolution mass spectrometer.
Nevertheless, several groups have reported that the QIT has full-scan detection limits similar to those of a quadrupole mass filter (QMF) operated in the selected-ion monitoring (SIM) mode for drug testing [4,5].
In 1996, the HP Model 5973 introduced the gold-plated hyperbolic quartz quadrupole mass filter, a breakthrough in instrument stability and performance.