pyruvate kinase


Also found in: Dictionary, Financial, Acronyms, Encyclopedia, Wikipedia.
Related to pyruvate kinase: pyruvate kinase deficiency

py·ru·vate ki·nase (PK),

phosphoenolpyruvate kinase; a phosphotransferase catalyzing transfer of phosphate from phosphoenolpyruvate to ADP, forming ATP and pyruvate; other nucleoside phosphates can participate in the reaction; a key step in glycolysis; a deficiency in pyruvate kinase will lead to hemolytic anemia.

pyruvate kinase

[pī′rəvāt]
an enzyme essential for anaerobic glycolysis in red blood cells. It catalyzes the transfer of a phosphate group from adenosine triphosphate to produce adenosine diphosphate.

py·ru·vate ki·nase

(PK) (pī'rū-vāt kī'nās)
A phosphotransferase catalyzing the transfer of phosphate from phosphoenolpyruvate to adenosine diphosphate, forming adenosine triphosphate and pyruvate; other nucleoside phosphates can participate in the reaction; a key step in glycolysis; pyruvate kinase deficiency leads to hemolytic anemia.

py·ru·vate ki·nase

(PK) (pī'rū-vāt kī'nās)
A phosphotransferase catalyzing the transfer of phosphate from phosphoenolpyruvate to adenosine diphosphate, forming adenosine triphosphate and pyruvate; other nucleoside phosphates can participate in the reaction; a key step in glycolysis; pyruvate kinase deficiency leads to hemolytic anemia.

pyruvate kinase (pīroo´vāt kī´nās´),

n an enzyme essential for anaerobic glycolysis in red blood cells.

pyruvate

a salt, ester or anion of pyruvic acid. The term is used interchangeably with pyruvic acid. Pyruvate is the end product of glycolysis and may be metabolized in the body to lactate or to acetyl CoA. In yeast it is metabolized to ethanol.

pyruvate carboxylase
an enzyme concerned in the conversion of pyruvate to oxaloacetic acid.
pyruvate dehydrogenase
actively concerned in the decarboxylation of pyruvate to acetyl CoA and CO2.
pyruvate kinase
a glycolytic pathway enzyme (called also PK) which catalyzes the formation of pyruvate from phosphoenolpyruvate (PEP). A deficiency of the enzyme is a hereditary defect in humans and occurs also in Beagle and Basenji dogs, causing a familial nonspherocytic anemia.
pyruvate transaminase
References in periodicals archive ?
The results from Chasmagnathus granulatus are in contrast to our results, as the pyruvate kinase level in the jaw muscle of crabs fed a high-CBH diet was 4-fold greater than in crabs fed a high-protein but low-CBH diet (Marqueze et al.
Insulinotropic effect of cinnamaldehyde on transcriptional regulation of pyruvate kinase, phosphoenol pyruvate carboxykinase and GLUT4 translocation in experimental diabetic rats.
Compared with the blank control, mogrosides treatment showed no effect on the expression of the pyruvate kinase coding gene pklr, while palmitic acid significantly reduced expression of pklr (P<0.
The activities of hexokinase, pyruvate kinase and glucose-6-phosphate dehydrogenase were significantly decreased whereas the activities of lactate dehydrogenase.
Test results for hemolysis remained negative, and glucose 6-phosphate deshydrogenase and erythrocyte pyruvate kinase levels 6 months after transfusion were within normal limits.
Seasonal change and prolonged anoxia affect the kinetic properties of phosphofructokinase and pyruvate kinase in oysters.
G6PD and pyruvate kinase concentrations were within reference intervals, and a presumptive diagnosis of hereditary elliptocytosis was made.
For example, our previous study (Chan et at, 2011) demonstrated that baicalein could significantly reverse the ciprofloxacin resistance of MRSA possibly by inhibiting the NorA efflux pump in vitro and inhibition of a newly discovered MRSA specific pyruvate kinase (PK) (Zoraghi et al.
Experiments with cultured rat astrocytes have also demonstrated that hypoxia induces cells to increase their glycolytic capacity, leading to an increase in the concentration of enzymes such as pyruvate kinase (23).
Tumor cells express their own characteristic isoform of the glycolytic key enzyme pyruvate kinase.
05) increased whereas hexokinase, pyruvate kinase, glucose-6-phosphate dehydrogenase and glycogen content significantly (p <0.

Full browser ?