pyruvate


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Related to pyruvate: Pyruvate dehydrogenase complex, Pyruvate kinase

pyruvate

 [pi´roo-vāt]
a salt, ester, or anion of pyruvic acid. Pyruvate is the end product of glycolysis and may be metabolized to lactate or to acetyl CoA.

py·ru·vate (Pyr),

(pī'rū-vāt),
A salt or ester of pyruvic acid.

pyruvate

/py·ru·vate/ (pi´roo-vāt) a salt, ester, or anion of pyruvic acid. Pyruvate is the end product of glycolysis and may be metabolized to lactate or to acetyl CoA.

pyruvate

(pī-ro͞o′vāt, pĭ-)
n.
A salt or an ester of pyruvic acid.

py·ru·vate

(pī'rū-vāt)
A salt or ester of pyruvic acid.
Pyruvic acidclick for a larger image
Fig. 264 Pyruvic acid . Molecular structure.

pyruvic acid

or

pyruvate

an important 3-carbon molecule formed from GLUCOSE and GLYCEROL in glycolysis (see Fig. 264 ). See also ACETYLCOENZYME A. Pyruvic acid is broken down further, the precise reactions depending upon whether oxygen is present or not. See AEROBIC RESPIRATION, ANAEROBIC RESPIRATION.

pyruvate (pī·rōōˑ·vāt),

n a biochemical involved in the Krebs cycle that facilitates ATP production. Has been claimed to assist in weight reduction by enhancing metabolism. No known precautions. Also called
sodium pyruvate, calcium pyruvate, potassium pyruvate, magnesium pyruvate, or
dihydroxyacetone pyruvate.

pyruvate

a salt, ester or anion of pyruvic acid. The term is used interchangeably with pyruvic acid. Pyruvate is the end product of glycolysis and may be metabolized in the body to lactate or to acetyl CoA. In yeast it is metabolized to ethanol.

pyruvate carboxylase
an enzyme concerned in the conversion of pyruvate to oxaloacetic acid.
pyruvate dehydrogenase
actively concerned in the decarboxylation of pyruvate to acetyl CoA and CO2.
pyruvate kinase
a glycolytic pathway enzyme (called also PK) which catalyzes the formation of pyruvate from phosphoenolpyruvate (PEP). A deficiency of the enzyme is a hereditary defect in humans and occurs also in Beagle and Basenji dogs, causing a familial nonspherocytic anemia.
pyruvate transaminase
References in periodicals archive ?
Increased blood lactate concentrations may also, especially in patients with sepsis, result from impaired clearance of lactate (4), inhibition of pyruvate dehydrogenase (5) and accelerated aerobic glycolysis6, at least in part related to activation of Na/K ATPase by endogenous or exogenous catecholamines (7,8).
7) MCT-1 is an embedded protein in the mitochondrial membrane that speeds the formation of pyruvate from lactate, thus making existing mitochondria more efficient.
05 per cent w/v sodium pyruvate incubated either under standard aerobic conditions, or under one of three different sets of anaerobic conditions i.
Archaeal pyruvate can produce histone deacetylase inhibition resulting in endogenous retroviral (HERV) reverse transcriptase and integrase expression.
Owing to concerns about their stability, acetoacetate, acetone, ascorbate, and pyruvate were supplemented into serum with within--reference interval and increased creatinine concentrations.
Its principal site of pharmacodynamic action is the mitochondrial pyruvate dehydrogenase (PDH) complex (Stacpoole 1989), a gatekeeper enzyme for regulating carbohydrate fuel metabolism in cells [see Supplemental Material, Figure 4 (doi:10.
Like glucose, pyruvate can also stimulate the nuclear maturation of porcine oocytes when it is added to NCSU37 medium (Funahashi et al.
It may be possible to design drugs that mildly suppress pyruvate kinase activity as a means of replicating the immune status of normal pregnancy," said Petty.
This lead to the successful testing of a small molecule inhibitor of pyruvate dehydrogenase kinase in animal tumors, and we now have approval to begin a clinical trial in patients with solid tumors.
Biotin is also essential for the function of pyruvate carboxylase, which plays a role in the conversion of pyruvate to oxaloacetate.