pyrroline-5-carboxylate reductase 1

pyrroline-5-carboxylate reductase 1

A housekeeping enzyme encoded by PYCR1 on chromosome 17q25.3 that catalyses the final step in proline biosynthesis using both NAD and NADP, and is involved in the cellular response to oxidative stress.
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The gene, pyrroline-5-carboxylate reductase 1, carries out the final step of proline synthesis.