pyrophosphatase


Also found in: Encyclopedia, Wikipedia.

pyrophosphatase

 [pi″ro-fos´fah-tās]
any enzyme that catalyzes the hydrolysis of central pyrophosphate linkages.

py·ro·phos·pha·tase

(pī'rō-fos'fă-tās),
Any enzyme catalyzing the hydrolysis of a pyrophosphate bond between two phosphoric groups, leaving one on each of the two fragments, for example, inorganic pyrophosphatase, NAD+ p. (cleaves NAD, etc., to mononucleotides), ATP pyrophosphatase (cleaves inorganic pyrophosphate from ATP, leaving AMP).
See also: flavin adenine dinucleotide.
Synonym(s): diphosphatase

pyrophosphatase

/py·ro·phos·pha·tase/ (-fos´fah-tās) any enzyme that catalyzes the hydrolysis of a pyrophosphate bond, cleaving between the two phosphate groups.

py·ro·phos·pha·tase

(pī'rō-fos'fă-tās)
Any enzyme cleaving a pyrophosphate bond between two phosphoric groups, leaving one on each of the two fragments.
Synonym(s): diphosphatase.

py·ro·phos·pha·tase

(pī'rō-fos'fă-tās)
Any enzyme cleaving a pyrophosphate bond between two phosphoric groups.
Synonym(s): diphosphatase.

pyrophosphatase (pir´ōfos´fətās´),

n an enzyme that cleaves an inorganic pyrophosphate from adenosyl triphosphate, leaving adenosine monophosphate.

pyrophosphatase

any enzyme that catalyzes the hydrolysis of central pyrophosphate linkages.
References in periodicals archive ?
In an in vitro reaction however, there's no pyrophosphatase around unless it's been added to the reaction, and so with each dNTP added to a nascent DNA, there's an additional PPi released into solution.
2004, Site-specific effects of zinc on the activity of family II pyrophosphatase, Biochemistry, 43, pp.
Chlorophyll, Hill activity, protein, RNA, dry weight, and activities of catalase and protease decreased, whereas free amino acid content, peroxidase activity, and the ratio of acid to alkaline pyrophosphatase activity increased (Sen & Mondal, 1987).
1988, "Separation and purification of the tonoplast ATPase and pyrophosphatase from plants with constitutive and inducible crassulacean acid metabolism," Planta, 175, pp.
Adverse drug reactions to azathioprine therapy are associated with polymorphism in the gene encoding inosine triphosphate pyrophosphatase (ITPase).
Parent LE, Mackenzie AF, Perron Y (1985a) Influence of four levels of pyrophosphatase activity on the rate of pyrophosphate hydrolysis in organic soils.
pumping pyrophosphatase (Shimmen & MacRobbie, 1987; Takeshige et al.
Dick WA, Juma NG, Tabatabai MA (1983) Effects of soils on acid pbosphatase and inorganic pyrophosphatase of corn roots.
Pyrosequencing involves use of a primer extension reaction, using a biotin-labeled single-stranded PCR amplicon as template, in which pyrophosphatase is released during the incorporation of each nucleotide in equimolar proportion to that incorporated.
The chromatographic separation contributes to a high analytical specificity, which is advantageous compared with former colorimetric procedures based on the quantification of inorganic phosphate after treatment with inorganic pyrophosphatase (23, 29, 34).
A reagent mixture containing 50 [micro]M deoxynucleotide triphosphate mixture (dCTP, dTTP, dGTP, and dATP-[alpha]S, treated with pyrophosphatase to remove contaminated pyrophosphate), 1.