pyrithiamine


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pyrithiamine

(pĭr″ĭ-thī′ă-mēn″)
A synthetic analog of thiamine that blocks thiamine transport. It was used experimentally in studies of human lymphoblasts to mimic nutritional diseases such as beriberi and Wernicke-Korsakoff syndrome, two forms of thiamine deficiency.
References in periodicals archive ?
In rat models of WE induced using pyrithiamine, the dominant MRS pattern is a reduction in both NAA and Cho in several brain regions (Lee et al.