pyrimidine


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pyrimidine

 [pĭ-rim´ĭ-dēn]
an organic compound that is the fundamental form of the pyrimidine bases, which include cytosine, thymine, and uracil.

py·rim·i·dine (Pyr),

(pī-rim'i-dēn),
1,3-Diazine; a heterocyclic substance, the formal parent of several "bases" present in nucleic acids (uracil, thymine, cytosine) as well as of the barbiturates.

pyrimidine

/py·rim·i·dine/ (pĭ-rim´ĭ-dēn) an organic compound, C4H4N2, the fundamental form of the pyrimidine bases, including uracil, cytosine, and thymine.

pyrimidine

(pī-rĭm′ĭ-dēn′, pĭ-)
n.
1. A single-ringed, crystalline organic base, C4H4N2, that is the parent compound of a large group of biologically important compounds.
2. Any of a group of substituted derivatives of pyrimidine, including the nitrogen bases uracil, cytosine, and thymine, which are components of nucleic acids. Barbiturates and certain other drugs are also pyrimidines.

pyrimidine

[pərim′ədēn]
an organic compound of heterocyclic nitrogen found in nucleic acids and in many drugs, including the antiviral drugs acyclovir, ribavirin, and trifluridine.

py·rim·i·dine

(pir-im'i-dēn)
A heterocyclic substance, the formal parent of several "bases" present in nucleic acids (uracil, thymine, cytosine) as well as of the barbiturates.

pyrimidine

A nitrogenous base compound. Two pyrimidines, cytosine and thymine, are the DNA bases which, with two PURINES, form the genetic code. A third pyrimidine, uracil, takes the place of thymine in RNA.

pyrimidine

one of three types of bases found in NUCLEIC ACIDS, with a single ring structure. DNA contains CYTOSINE and THYMINE, RNA contains cytosine and URACIL. Pyrimidines always pair with PURINES in DNA.

pyrimidine

an organic compound that is the fundamental form of the pyrimidine bases, including uracil, cytosine and thymine.

A pyrimidine
cytosine.
References in periodicals archive ?
This is supported by the observation that one of these enzymes, DNA polymerase eta (Pol [eta]), supports accurate DNA replication past pyrimidine dimers in vitro.
Co-Existence of Hereditary Pyrimidine 5'-Nucleotidase Deficiency and Heterozygous a-Thalassemia: A Case Presentation.
The de novo pyrimidine biosynthesis enzymes offer potential as targets for drug design because unlike the host, the parasite does not have pyrimidine salvage pathways (Bladwin 2005).
During photo-reactivation, the photo-reactivating enzyme (PRE) binds to the cyclobutane-type pyrimidine dimers formed by DNA irradiated with low wavelength UV (<320 nm; Sutherland 1981, Setlow 1995).
TS-1/S-1 is an oral pyrimidine fluoride-derived anticancer agent which has been available in Japan since 1999.
The activities of pyrimidine nucleotidase (P5'N) and nicotinamide adenine dinucleotide synthase (NADS) are also modified in blood after Pb exposure.
Leflunomide, a pyrimidine synthesis inhibitor, causes dose-related teratogenicity and toxicity in animals at doses much lower than those used in humans.
5' propynyl-modified pyrimidine nucleotides (shown in bold) were positioned at universally conserved positions within these primers to extend the breadth of broad-range priming to allow efficient PCR from all CoV species tested.
Charnley adds that his group is now in hot pursuit of a pyrimidine, a particular component of DNA and RNA.
The CYC400 CDK inhibitor series has emerged from a pyrimidine basic chemical structure or pharmacophore.
Enzymatic photoreactivation is a direct mechanism to repair UV-induced cyclobutane pyrimidine dimers.