pyridoxal 5'-phosphate

Also found in: Encyclopedia.

pyr·i·dox·al 5'-phos·phate (PLP),

a coenzyme essential to many reactions in tissue, notably aminotransfers and amino acid decarboxylations.

pyr·i·dox·al 5'-phos·phate

(pir-i-doks'ăl fos'fāt)
A coenzyme essential to many reactions in tissue, notably transaminations and amino acid decarboxylations.
References in periodicals archive ?
Vitamin B6 as pyridoxal 5'-phosphate, 100 to 200 mg
Pyridoxal 5'-phosphate is needed during exercise for gluconeogenesis and for glycogenolysis in which it serves as a cofactor for glycogen phosphorylase (21).
Prohibit the marketing of dietary supplements containing pyridoxal 5'-phosphate [docket on the Internet].
Plasma pyridoxal 5'-phosphate in the US population: the National Health and Nutrition Examination Survey, 2003-2004.
Its major active forms in animals are pyridoxal 5'-phosphate (PLP) and pyridoxamine 5'-phosphate (PMP).
The enzyme consists of two identical monomers and a tightly bound co-factor pyridoxal 5'-phosphate (Rolland et al.
Because superoxide, peroxynitrite, as well as advanced glycation end-products are formed in both microvasculature and neural tissues of the peripheral nervous system, methylcobalamin and pyridoxal 5'-phosphate are likely to act on multiple cell types.
Pyridoxal 5'-phosphate is an active form of vitamin B625 that is receiving growing attention as a natural complement to benfotiamine.
Folate (5-methyltetrahydrofolate), riboflavin, flavin mononucleotide (FMN), [7] FAD, pyridoxal 5'-phosphate (PLP), pyridoxal (PL), pyridoxic acid, free choline, betaine, dimethylglycine, creatinine, methionine sulfoxide, arginine, asymmetric dimethylarginine (ADMA), symmetric dimethylarginine (SDMA), tryptophan, kynurenine, kynurenic acid, anthranilic acid, 3-hydroxykynurenine, xanthurenic acid, 3-hydroxyanthranilic acid, and formiminoglutamic acid, were determined by liquid chromatography--tandem mass spectrometry (14-17), and methylmalonic acid, total homocysteine, total cysteine, methionine, serine, glycine, cystathionine, and sarcosine by gas chromatography-tandem mass spectrometry (15, 18).
It also turns out that some upstart drug company got the idea that it owns God's molecule, pyridoxal 5'-phosphate (PLP; the biologically active form of vitamin B6).
The synthesis of serotonin and the catecholamines requires participation of 2 cofactors, tetrahydrobiopterin (BH4) for the activity of tyrosine hydroxylase and tryptophan hydroxylase and pyridoxal 5'-phosphate (PLP) for the activity of aromatic L-amino acid decarboxylase (AADC) (Fig.