pyridostigmine


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pyridostigmine

 [pir″ĭ-do-stig´mēn]
an anticholinesterase; used as the bromide salt in the treatment of myasthenia gravis and as an antidote to nondepolarizing neuromuscular blocking agents such as tubocurarine.

pyridostigmine

/pyr·i·do·stig·mine/ (pir″ĭ-do-stig´mēn) a cholinesterase inhibitor, used as the bromide salt in the treatment of myasthenia gravis and as an antidote to nondepolarizing neuromuscular blocking agents.

Mestinon

An oral agent used to manage myasthenia gravis.

Adverse effects
• Muscarinic—Nausea, vomiting, diarrhoea, abdominal cramps, increased peristalsis, increased salivation, increased bronchial secretions, miosis, diaphoresis; reversed with atropine.
• Nicotinic—Muscle cramps, fasciculation and weakness.

pyridostigmine

Mestinon® Pharmacology A cholinergic used to manage Pts with myasthenia gravis, including crises Adverse effects ↑ salivation, fasciculation, abdominal cramps, diarrhea. See Reversal agent.

pyridostigmine

A CHOLINERGIC drug used in the treatment of MYASTHENIA GRAVIS. The drug is on the WHO official list. A brand name is Mestinon.

pyridostigmine

a cholinesterase inhibitor; used as the bromide in the treatment of myasthenia gravis and as an antidote to nondepolarizing muscle relaxants, e.g. tubocurarine.
References in periodicals archive ?
In conclusion, the use of immunosuppression in juveniles with generalised MG not responding to pyridostigmine alone, is associated with a good remission rate.
The drug, Pyridostigmine, is currently approved for use in treating certain cases of muscle weakness.
Now, 17 years after the Gulf War, the congressionally mandated Research Advisory Committee on Gulf War Veterans' Illnesses has officially released a 450-page report which confirms that Gulf War Illness is a result of soldiers' exposure to neurotoxic chemicals, including pyridostigmine bromide and pesticides.
It's been a long time coming for veterans whose health complaints have been met with skepticism, but a federal panel has determined that Gulf War syndrome is not only real, it is tied to two causes: exposure to pyridostigmine bromide and certain pesticides during the 1990-1991 Persian Gulf War.
An open trial of pyridostigmine in post-poliomyelitis syndrome.
It's been a long time coming for veterans whose health complaints have been met with skepticism, but a federal committee has determined that Gulf War syndrome is not only real, it is tied to two causes: exposure to pyridostigmine bromide and certain pesticides during the 1990-1991 Persian Gulf War.
1) The use of the nerve-agent pretreatment pyridostigmine created a similar controversy following the Persian Gulf conflict of 1991 because of the medication's wide use for what is generally referred to as an "off-label" indication.
Summary of: Jones KD, Burckhardt CS, Deodhar AA, Perrin NA, Hanson GC, Bennett RM (2008) A six-month randomized controlled trial of exercise and pyridostigmine in the treatment of fibromyalgia.
In a subsequent study, although pyridostigmine pretreatment significantly improved survival, clonidine and not pyridostigmine was able to inhibit the signs of central toxicity of soman (63), suggesting a centrally mediated effect of clonidine.