pyridinium collagen crosslinks

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Metabolic disease A family of molecules that links collagen fibers to each other; the breakdown products are excreted in the urine with attached crosslinks including pyridinoline–PYD and deoxypyridinoline–DPYD; ↑ DPYD and PYD indicate bone matrix degradation and resorption, osteoporosis, primary hyperparathyroidism, Paget's disease. See Osteoporosis; Cf N-telopeptides.

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