The pinworm medicine features pyrantel
pamoate, the only O-T-C anthelmintic that has been recognized to date by the FDA.
A total of 5 captive wild carnivores (lion-1, leopards2, hyaena-1 and jackal-1) suffering from moderate to heavy helminthic infection (EPG ranging from 600-1800) were treated with Prazisam plus (a) tablets (each tablet having Fenbendazole-500mg, Pyrantel
pamoate-144mg and Praziquantel-50mg) @ 1tab/ 10 kg.
Baits were similar to oral rabies vaccine baits and consisted of a hollow fishmeal polymer food attractant (15 g, 33 mm x 32 mm x 21 mm) in which we placed 180 mg (base) of pyrantel
pamoate mixed with marshmallow creme, which was sealed within the hollow chamber with paraffin wax.
As just a few examples, milbemycin oxime and moxidectin are included in a number of heartworm preventive drugs, and are also credited with effectiveness against roundworms, hookworms, and whipworms; pyrantel
pamoate (the "plus" in Heartgard Plus) is effective against roundworms and hookworms only.
A single dose of pyrantel
pamoate at a dose of 10 mg/kg body weight was administered to subjects with helminth ova in a diarrhoeal stool sample (mebendazole is contraindicated in children aged under 2 years).
Hadju V, Stephenson LS, Abadi K, Mohammed HO, Bowman DD and RS Parker Improvements in appetite and growth in helminth-infected schoolboys three and seven weeks after a single dose of pyrantel
Parasites were treated in children over two years of age via 100 mg of mebendazol; using pyrantel
pamoate in children under two years of age.
Patients with pinworm infection are initially treated with 1 dose of oral mebendazole (100 mg), albendazole (400 mg), or pyrantel
pamoate (11 mg/kg, maximum dose 1 g) (strength of recommendation [SOR] B).
3 ml recommended for neonates (0 - 6 months), 5 ml prescribed 5 ml/d recommended for children, 15 ml/d prescribed Folic acid 2 - 5 mg per day recommended for children 1 - 5 years, 15 mg/d prescribed Pyrantel
pamoate 2 tablets or 5 ml suspension recommended for children 2 - 6 years, 10 ml single dose prescribed for 2-year-old child Vitamin C 100 - 200 mg/24 h recommended, 300 mg/24 h frequently prescribed Promethazine 5 - 15 mg recommended for children 2 - 5 years, 37.
The fact that tribendimidine is different from albendazole, but has the same level of effectiveness, and is in the same class as pyrantel
and levamisole should increase people's comfort level in using this new drug," said Aroian.
A combination product of praziquantel, pyrantel
pamoate, and febantel has been shown to decrease cyst excretion in infected dogs.
The best method of deworming against tapeworms is to use a high dose of pyrantel