pyramidal cell


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Related to pyramidal cell: Apical dendrite

pyramidal cell

Etymology: Gk, pyramis + L, cella, storeroom
a neuron with a pyramid-shaped cell body in the gray matter of the cerebral cortex.

pyramidal cell

A large, common neuron found in the cerebral cortex. Pyramidal cells are flask-shaped or triangular, and, in the parts of the cortex with six layers, they occupy the fifth layer. Pyramidal cell dendrites project up into the most superficial layer of the cortex, while pyramidal cell axons run in the opposite direction, i.e., downward and out of the cortex.
Synonym: pyramidal neuron
See also: cell
References in periodicals archive ?
The present study showed sex difference in pyramidal cell number in the subiculum, in favour of the males.
In addition to suppressing the output from pyramidal cells, alcohol has several other effects on hippocampal function.
Recent data suggest that administering MK-801, a compound that blocks receptors for the brain chemical glutamate, during alcohol withdrawal reduces the loss of hippocampal pyramidal cells in the CA1 region in a neonatal rat model.
This work would provide detailed micro-circuit models of mice V1 and S1 superficial layers responsible for the emergence and modulation of pyramidal cells sensory responses.
These include differences in the number of spines on the apical dendritic shafts of CA3 pyramidal cells (22), as well as differences in the number of mossy fiber synapses to these cells (23).
While body of evidences pointed to the prefrontal cortex (PFC) as a key structure for cognition, recent studies further suggested that abnormalities in the interaction between inhibitory interneurons and glutamatergic pyramidal cells within PFC microcircuit could be involved in the pathogenesis of cognitive deficits in psychiatric disorders.
Furthermore, our model shows that the inhibitory connection from interneurons to pyramidal cells serve as an important site for the storage of extinction memory," he added.
This paper presents the effects of eugenol on the AMPA and NMDA-mediated synaptic transmission between the Schaffer collaterals and the CA1 pyramidal cells of the rat hippocampal slices.
Specifically, the researchers examined the spiny neurons in the nucleus accumbens and the pyramidal cells in the parietal cortex.
42] fragment induces apoptosis and is found inside of the hippocampal pyramidal cells (on the RER, nucleus and mitochondria).
Electrophysiological recordings were made from visually identified interneurons and pyramidal cells using current/voltage clamp techniques.