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any purulent skin disease.
pyoderma gangreno´sum a rapidly evolving cutaneous ulcer or ulcers, with undermining of the border. Once regarded as a complication peculiar to ulcerative colitis, it is now known to occur in other wasting diseases.
a chronic, noninfective eruption of spreading, undermined ulcers showing central healing, with diffuse dermal neutrophil infiltration; often associated with ulcerative colitis.
a rapidly evolving, idiopathic, chronic debilitating skin disease that usually accompanies a systemic disease, especially chronic ulcerative colitis, and is characterized by irregular, boggy, blue-red ulcers with undermined borders surrounding purulent necrotic bases.
pyoderma gangrenosumAn uncommon idiopathic condition which begins as papules and pustules in the follicles, followed by a rapidly expanding necrotic ulcer measuring 3 to 30 cm and rimmed by violaceous erythema. At least half of patients have associated systemic disease, including infection, malignancy, vasculitis, collagen vascular disease, diabetes, or trauma; it may have an autoimmune component.
An initial bite-like lesion, pain, arthralgias and malaise; the classic ulcers occur on the legs; a superficial variant—atypical PG—tends to occur on the hands; involvement of other organ systems manifests as sterile neutrophilic abscesses in the lungs, heart, CNS, GI tract, eyes, liver, spleen, bone, and lymph nodes.
IBD—either ulcerative colitis or Crohn’s disease, asymmetric polyarthritis, hematologic disorders (e.g., leukaemia or preleukaemia), predominantly myelocytic, monoclonal gammopathies, especially IgA gammopathy. Less common associations include arthritides (e.g., psoriatic arthritis, osteoarthritis, or spondyloarthropathy), liver disease (e.g., hepatitis and primary biliary cirrhosis), myeloma (especially IgA type) and immunologic diseases (e.g., SLE, Sjögren syndrome).
Ulcers due to infection, malignancy, stasis, vasculitis, necrotising fasciitis, acute febrile neutrophilic dermatosis, aphthous stomatitis, atrophie blanche, Behçet disease, chancroid, Churg-Strauss syndrome (allergic granulomatosis), ecthyma gangrenosum, herpes simplex, hypersensitivity vasculitis (leukocytoclastic vasculitis), impetigo, insect bites, sporotrichosis, squamous cell carcinoma, venous insufficiency, verrucous carcinoma, Wegener’s granulomatosis.
Anti-inflammatories (e.g., corticosteroids), immunosuppressants.
pyoderma gangrenosumDermatology A rare idiopathic condition characterized by skin ulceration; at least 50% of Pts have associated systemic disease, including infection, malignancy, vasculitis, collagen vascular diseases, DM, trauma Clinical An initial bite-like lesion, pain, arthralgias and malaise; the classic ulcers occur on the legs; a superficial variant, atypical PG, tends to occur on the hands; involvement of other organ systems manifests as sterile neutrophilic abscesses in the lungs, heart, CNS, GI tract, eyes, liver, spleen, bone, and lymph nodes Associated conditions IBD–either ulcerative colitis or Crohn's disease, a symmetric polyarthritis, hematologic disorders–eg, leukemia or preleukemia, predominantly myelocytic, monoclonal gammopathies, especially IgA gammopathy; less common associations include arthritides–eg, psoriatic arthritis, osteoarthritis, or spondyloarthropathy; liver disease–eg, hepatitis and primary biliary cirrhosis; myeloma–especially IgA type and immunologic diseases–eg, SLE, Sjögren's DiffDx Acute febrile neutrophilic dermatosis, aphthous stomatitis, atrophie blanche, Behçet disease, chancroid, Churg-Strauss syndrome–allergic granulomatosis, ecthyma, ecthyma gangrenosum, herpes simplex, hypersensitivity vasculitis–leukocytoclastic vasculitis, impetigo, insect bites, sporotrichosis, SCC, venous insufficiency, verrucous carcinoma, Wegener's granulomatosis Management Anti-inflammatories–eg, corticosteroids, immunosuppressants
py·o·der·ma gan·gre·no·sum(pī'ō-dĕr'mă gang-grĕ-nō'sŭm)
A chronic, noninfective eruption of spreading, undermined ulcers showing central healing, with diffuse dermal neutrophil infiltration; often associated with ulcerative colitis.
A rare, ulcerating skin disease in which the skin is infiltrated by neutrophils. It is often found in people with other underlying illnesses, such as inflammatory bowel disease, rheumatoid arthritis, or some hematological malignancies.See: illustration
See also: pyoderma
pyoderma gangrenosumA rare disease featuring areas of gangrene of the skin, mainly affecting the legs. In spite of the name, the condition is not of infective origin. It occurs in a small percentage of people with ULCERATIVE COLITIS.
pyoderma gangrenosumerythematous nodules/pustules, which may progress to large spreading ulcers (with blue-black undermined edge and pus-like surface); of unknown cause; may arise idiopathically, but is strongly associated with e.g. inflammatory bowel disease, rheumatoid arthritis, myeloma, leukaemia, liver disease; treatment includes steroids and immunosuppressive drugs
any purulent skin disease. Includes pustule, pimple, acne, impetigo and furunculosis.
see callus pyoderma.
contagious porcine pyoderma
see contagious porcine pyoderma.
bacterial infections involving the dermis and often subcutaneous tissues. There may be systemic illness.
see zinc-responsive dermatosis.
a rapidly evolving cutaneous ulcer or ulcers, with undermining of the border.
infection of the interdigital skin in dogs; may be associated with trauma, Demodex canis infestation, or foreign bodies such as grass seeds.
a sterile, pustular skin disease on the face and head and sometimes ears, anus and prepuce, in one or more puppies of a litter, usually around weaning age. Dachshunds, Golden retrievers and Gordon setters appear to be predisposed. There is often fever, anorexia and lymphadenopathy, particularly of submandibular lymph nodes which may form abscesses and drain, hence the alternative name of puppy strangles. Staphylococcus spp. are frequently cultured from affected skin, but the etiology of the disease is unclear. Called also juvenile cellulitis, and juvenile sterile granulomatous dermatitis and lymphadenitis.
occurs on the lip margins and perioral skin of dogs; German shepherd dogs are predisposed.
a deep bacterial folliculitis and furunculosis on the dorsum of the nose in dogs, particularly German shepherd dogs, Bull terriers, Collies and Pointers. Trauma may be a factor in the etiology.
see perianal fistula.
pressure point pyoderma
see pressure points.
superficial pustular pyoderma
see acute moist dermatitis.
tail fold pyoderma