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pyloric gland

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pyloric gland
n.
Any of several coiled, tubular, mucus-secreting glands situated in the mucus membrane near the pyloric end of the stomach.

pyloric
pertaining to the pylorus or to the pyloric part of the stomach.

antral pyloric hypertrophy syndrome
a narrowing of the pyloric antrum caused by hypertrophy of the circular smooth muscle and mucosa; occurs most commonly in dogs of small breeds. Obstruction to gastric emptying causes chronic vomiting.
pyloric antrum
the part of the stomach cavity just cranial to the pylorus.
pyloric dysfunction
the usual effect is to delay gastric emptying. See pyloric achalasia, pyloric obstruction (below).
pyloric gastropathy
chronic hypertrophic pyloric gastropathy.
pyloric gland
situated in the pyloric region of the stomach and secreting gastrin and mucus. The secretion is slightly alkaline.
pyloric obstruction
may be functional due to spasm or achalasia, or physical due to foreign body, e.g. phytobezoar, or external compression by, e.g. lipoma or fat necrosis or tumor or cicatrical contraction. Clinical signs are vomiting, distress due to gastric dilatation, possibly visible abdominal enlargement. In ruminants gross distention of abdomen, rumen contents running from nose, scant feces. In dogs and cats delayed gastric emptying usually causes vomiting, sometimes characteristically projectile, of undigested food.
pyloric outflow failure
achalasia of the pylorus with obstruction to the flow of ingesta into the intestine; impaction of material in the abomasum follows; pyloric ulcer a common sequel.
pyloric spasm
see pyloric achalasia (above).
pyloric stenosis, congenital pyloric hypertrophy
usually a congenital lesion in dogs, particularly the brachycephalic breeds, that causes vomiting and poor growth from weaning age. Occasionally hypertrophy of the pyloric sphincter may be acquired.


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A recent study26 reported altered mucin expression in reactive gastropathy, including aberrant expression of MUC5Ac in pyloric glands.
Samples submitted for histopathologic examination included brainstem, trigeminal ganglia, tonsils, pyloric gland area of the stomach, jejunum, ileum, lymph nodes, heart, spleen, liver, kidneys, and lung.
Aberrant expression of MUC5AC in pyloric glands was observed in 81% of the cases, and aberrant expression of MUC6 in the upper foveolar epithelium was diffusely seen in 14% of the cases.
 
 
 
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