pyknosis


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Related to pyknosis: karyolysis, karyorrhexis

pyknosis

 [pik-no´sis]
a thickening, especially the degeneration of a cell in which the nucleus shrinks in size and the chromatin condenses to a solid, structureless mass or masses. adj., adj pyknot´ic.

pyk·no·sis

(pik-nō'sis),
A thickening or condensation; specifically, a condensation and reduction in size of the cell or its nucleus, usually associated with hyperchromatosis; nuclear pyknosis is a stage of necrosis.
[pykno- + G. -osis, condition]

pyknosis

/pyk·no·sis/ (pik-no´sis) a thickening, especially degeneration of a cell in which the nucleus shrinks in size and the chromatin condenses to a solid, structureless mass or masses.pyknot´ic

pyknosis

[piknō′sis]
the condensation of nuclear material into a solid, darkly staining mass in a dying cell thickness, especially shrinking of cells through degeneration.
enlarge picture
Pyknosis

pyk·no·sis

(pik-nō'sis)
A thickening or condensation; specifically, a condensation and reduction in the size of the cell or its nucleus, usually associated with hyperchromatosis; nuclear pyknosis is a stage of necrosis.
[pykno- + G. -osis, condition]

pyk·no·sis

(pik-nō'sis)
A thickening or condensation; specifically, a condensation and reduction in the size of the cell or its nucleus, usually associated with hyperchromatosis.
[pykno- + G. -osis, condition]

pyknosis (piknō´sis),

n increased basophilia and shrinkage of the nucleus of a dying cell.

pyknosis

a thickening, especially degeneration of a cell in which the nucleus shrinks in size and the chromatin condenses to a solid, structureless mass or masses.
References in periodicals archive ?
The toxic chemical substances including mycotoxins (Bokhari and Ali, 2008) were excreted via distal tubules resulting in degenerative necrotic changes and this what was observed here where marked tubular necrosis was found to be associated with presence of hyaline casts cells inflammatory cell, and nuclear pyknosis.
ONL nuclear deformations (arrows) were observed in (A) control ONL nucleus and as (B) nucleolus condensation, (C) karyolysis, (D, E pyknosis, and (F) karyorrhexis.
Necrosis of the epithelium of proximal convoluted tubules was characterized by pyknosis, karyorhexis and karyolysis.
These inclusions were sometimes associated with nuclear pyknosis and karyorrhexis, but again no etiological agent was detected.
18,25) Oligodendrocyte pyknosis and apoptosis, features observed in Pattern 3 pathology, (21) are present in evolving lesions derived from patients whose brains are examined shortly after or during an exacerbation of MS.
Apoptosis is a highlyregulated process that is morphologically characterized by cell shrinkage, nuclear pyknosis, chromatin condensation, fragmentation of DNA, changes to the distribution of specific lipids within the plasma membrane, and blebbing of the plasma membrane (Danial & Korsmeyer, 2004).
Prenecrotic changes, including pyknosis and cellular swelling, were observed in connective tissue cells, and necrosis of both connective tissue and oocytes (atresia) was observed in several instances.
The enterotoxin is tight-junction specific; causes rounding, swelling, and pyknosis of cultured enterocytes; and induces a fluid response in ligated intestinal loops and a cytotoxic response in the HT-29 colon cell line (7).
The changes observed included vacuolation, irregular spindle shapes, lack of cell aggregates and occasional pyknosis.
S3A, B and C, the typical apoptotic appearance, such as cell shrinkage and pyknosis, was observed in PepE treated gastric cancer cells, indicating that PepE may cause gastric cancer cell death by inducing cell apoptosis.
Perry, "Astrocytosis, microglia activation, oligodendrocyte degeneration, and pyknosis following acute spinal cord injury," Experimental Neurology, vol.