DDX41

(redirected from putative RNA helicase)

DDX41

A gene on chromosome 5q35.3 that encodes a protein with a conserved Asp-Glu-Ala-Asp—DEAD motif, which is a probable ATP-dependent RNA helicase. It is required during post-transcriptional gene expression, and may be involved in pre-mRNA splicing.
References in periodicals archive ?
The inv(11)(p15q22) chromosome translocation of de novo and therapy-related myeloid malignancies results in fusion of the nucleoporin gene, NUP98, with the putative RNA helicase gene, DDX10.
The nature of these sensors has remained unknown until recently, when 2 putative RNA helicases, RIG-I and MDA5, were identified as sensors for viral dsRNA generated in the cytoplasm during viral infection (2-4).
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