pustular psoriasis

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Related to pustular psoriasis: guttate psoriasis

pus·tu·lar pso·ri·a·sis

1. an extensive exacerbation of psoriasis, with pustule formation in the normal and psoriatic skin, fever, and granulocytosis; sometimes precipitated by oral steroids; Synonym(s): generalized pustular psoriasis of Zambusch
2. a local pustular eruption of the palms and soles, occurring most commonly in a patient with psoriasis; difficult to distinguish from acrodermatitis continua.

pustular psoriasis

Etymology: L, pustula, blister; Gk, psoriasis, itch
a severe form of psoriasis consisting of bright red patches and sterile pustules all over the body. Crops of lesions lasting 4 to 7 days occur every few days in cycles over weeks or months. Recurrences are inevitable. Fever, leukocytosis, and hypoalbuminemia are associated. In rare cases, hypovolemia and kidney failure occur. Hospitalization may be necessary for fluid replacement, steroid therapy, and sedation. Compare guttate psoriasis. See also psoriasis.
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Pustular psoriasis


Leo von, 20th century German physician.
generalized pustular psoriasis of Zambusch - an extensive exacerbation of psoriasis. Synonym(s): pustular psoriasis


chronic skin condition, characterized by circumscribed, discrete and confluent, crimson red, silver-scaled, plaque-like inflammatory skin lesions, affecting 2% of population; exacerbated by stress, drugs (e.g. non-steroidal anti-inflammatory drugs, beta-blockers, angiotensin-converting enzyme inhibitors, lithium, alcohol, hydroxyquinoline), streptococcal infections, and trauma (due to Koebner phenomenon); plaques show local epidermal thickening, hypervascularity, abnormality of T-lymphocyte function, proliferation and altered differentiation of keratinocytes and parakeratosis; lesions characteristically affect extensor surfaces, scalp and trunk; nails become dystrophic, showing onycholysis, subungual hyperkeratosis and thimble pitting; small joints of hands and feet may develop psoriatic arthropathy; treated by systemic cytotoxic drugs (e.g. methotrexate, ciclosporin, azathioprine, efalizumab, hydroxycarbamide) and acitretin or topical applications, e.g. emollients, for mild presentations; coal tar ointments and balms; vitamin D analogue ointment (e.g. calcipotriol); dithranol, phototherapy (using ultraviolet B), photochemotherapy (using psoralens and long-wave ultraviolet light [PUVA])
  • guttate psoriasis widely scattered, multiple psoriatic lesions; distribution resembles raindrops on a dry pavement; characteristically develops after streptococcal throat infection

  • pustular psoriasis formation of sterile 'pustules' often of plantar skin; associated with generalized psoriasis

References in periodicals archive ?
There are no trials of methotrexate efficacy for palmoplantar pustular psoriasis.
Over the next 2 years, the patient received 5 mg/kg of intravenous infliximab every 7-8 weeks; this was increased to every 6 weeks to manage a gradual return of his pustular psoriasis.
Based on the clinical presentations, it is classified into four groups as follows: psoriasis vulgaris (PsV), arthritic psoriasis, pustular psoriasis (PP), and erythrodermic psoriasis.
Impetigo herpetiformis is not related to bacterial or viral causes, but is rather a manifestation of pustular psoriasis during pregnancy.
If you suspect ACE inhibitor involvement, "talk with the patient's internist about switching medications," he said, noting one caveat: "Often the first words out of the internist's mouth are "let's put them on one of these new angiotensin receptor antagonists," which may not be a good idea because there has been at least one report linking those to the development of pustular psoriasis.
CHICAGO -- Evidence is mounting that biologic therapies such as alefacept and efalizumab can successfully treat palmoplantar pustular psoriasis.
You should not use Taclonex[R] Ointment or Taclonex Scalp[R] Topical Suspension if you are allergic to any of their ingredients, have thin skin (atrophy) at the treatment site, have known or suspected calcium metabolism disorders (too much or too little calcium in your blood or urine), have erythrodermic, exfoliative, or pustular psoriasis, or have severe kidney or severe liver disease.
Based on clinical findings, our differentials were following: chronic eczema, pustular psoriasis, hypertrophic LP, erythema elevatum diutinum and necrolytic acral erythema.
1) It appears to be beneficial for pustular psoriasis.
Erythroderma, arthropathy, localized and generalized forms of pustular psoriasis are quite rare in contrast to guttat psoriasis.