purine-nucleoside phosphorylase

pur·ine-nu·cle·o·side phos·phor·y·lase

a ribosyltransferase that reversibly catalyzes the phosphorolysis of a purine nucleoside with orthophosphate to produce a purine and α-d-ribose 1-phosphate; an inherited deficiency of this enzyme leads to cellular immunodeficiency.
References in periodicals archive ?
1]H-NMR, proton nuclear magnetic resonance; CSF, cerebrospinal fluid; TSP, trimethylsilyl-2,2,3,3-tetradeuteropropionic acid, sodium salt; SAICA, succinylaminoimidazole carboxamide; APRT, adenine phosphoribosyltransferase; XDH, xanthine dehydrogenase; AO, aldehyde oxidase; HGPRT, hypoxanthine-guanine phosphoribosyltransferase; ADA, adenosine deaminase; and PNP, purine-nucleoside phosphorylase.

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