purine metabolism


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purine metabolism

Metabolism involving nucleic acids, present in nuclei of cells, in which they are combined with proteins to form nucleoproteins. In the breakdown of nucleic acid, uric acid, a nitrogenous waste product, is formed.
See also: metabolism
References in periodicals archive ?
Recent data from UCSD researchers indicates that there is a subset of patients diagnosed with autism who have abnormal purine metabolism," continued Dr.
An additional advantage over previous methods is the inclusion of uric acid and 2,8-dihydroxyadenine because hyper- and hypouricemia are important in establishing diagnoses of 5 different disorders of purine metabolism (2).
Allopurinol-treated patients had lower uric acid, xanthine, and hypoxanthine concentrations, as expected from the action of allopurinol on purine metabolism.
Decreased Sadenosylhomocysteine hydrolase in inborn errors of purine metabolism.
APRT deficiency was the only enzyme defect in purine metabolism where no abnormality could be observed in the urinary [sup.