purine


Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.
Related to purine: uric acid, low purine diet

purine

 [pu´rēn]
a heterocyclic compound that is the nucleus of the purine bases such as adenine and guanine (which occur in DNA and RNA), and xanthine and hypoxanthine.

pur·ine (Pur),

(pyūr'ēn, -rin),
The parent substance of adenine, guanine, and other naturally occurring purine "bases."

purine

/pu·rine/ (pūr´ēn) a compound, C5H4N4, not found in nature, but variously substituted to produce a group of compounds, purines or purine bases, which include adenine and guanine found in nucleic acids and xanthine and hypoxanthine.

purine

(pyo͝or′ēn′)
n.
1. A double-ringed, crystalline organic base, C5H4N4, that is the parent compound of a large group of biologically important compounds.
2. Any of a group of substituted derivatives of purine, including the nitrogen bases adenine and guanine, which are components of nucleic acids. Uric acid, caffeine, theobromine, and theophylline are also purines.

purine

[pyo̅o̅′rēn]
Etymology: L, purus, pure, urina, urine
any one of a large group of nitrogenous compounds. Purines are produced as end products in the digestion of certain proteins in the diet, but some are synthesized in the body. Purines are also present in many medications and other substances, including caffeine, theophylline, and various diuretics, muscle relaxants, and myocardial stimulants. Hyperuricemia may develop in some people as a result of an inability to metabolize and excrete purines. A low-purine diet or a purine-free diet may be required. Foods that are high in purines include anchovies and sardines; sweetbreads, liver, kidneys, and other organ meats; legumes; and poultry. The foods lowest in purine content include eggs, fruit, cheese, nuts, sugar, gelatin, and vegetables other than legumes.

pu·rine

(pyūr'ēn)
The parent substance of adenine, guanine, and other naturally occurring so-called purine bases; not known to exist as such in mammals.

purine

one of two types of base found in NUCLEIC ACIDS, having a double ring structure; see ADENINE and GUANINE. Purines always pair with PYRIMIDINES in the two strands of DNA, ensuring a parallel-sided molecule.

Purine

A white crystalline substance that is one of the building blocks of DNA. Uric acid is produced when purine is broken down in the body.
Mentioned in: Gout, Uric Acid Tests

purine

a heterocyclic compound that is the nucleus of the purine bases (or purines) such as adenine and guanine, which occur in DNA and RNA, and xanthine and hypoxanthine. All living cells contain purines as purine nucleotides. They can be synthesized using amino acids, or by salvage of dietary or endogenous nucleotides derived from cell wastage.

A purine
adenine.
low purine diet
one with a low content of organ meats, seafood, beans, lentils, peas and spinach; used in the dietary management of xanthine or urate uroliths in dogs.
purine nucleoside phosphorylase
a transferase enzyme that acts in the degradation of nucelotides and nucleic acids.
References in periodicals archive ?
The separation of pure purine compounds added to blank serum is shown in Fig.
Uric acid is a waste product of substances called purines, which are normally excreted through urine.
The bases concentrations with exclusion guanine and purine were changed by time of sampling.
For the simultaneous determination of pyrimidines and purines, HPLC is more frequently used, but capillary GC is free from use of expensive solvents and their disposal.
Purine derivative excretion in dairy cows: Endogenous excretion and the effect of exogenous nucleic acid supply.
Mean daily excretion of purine derivatives and microbial nitrogen compounds by dairy cows in different experimental diets.
By inhibiting PNP, the drug BCX4945 kills the parasites by starving them of the purines they need to survive.
Analysis method for determining uric acid and allantoin and synthesized microbial protein from excreted purine derivatives in the urine:
Only 6 to 8 percent of all uroliths are urate or purine stones, but their presence in certain breeds is significant.
While investigating how Leishmania becomes resistant to toxic purine nucleosides, we identified and cloned the TOR gene [1,2].