pulmonary blastoma

pulmonary blastoma

A biphasic CA of older adults Clinical Primitive
mesenchymal stroma with a myxoid appearance, ± mature mesenchymal elements–eg, cartilage and malignant epithelial component reminiscent of fetal lung tissue or secretory endometrium Prognosis Poor; most Pts die. Cf Pleuropulmonary blastoma.
References in periodicals archive ?
Michael's mum Sonia recalled how he was first diagnosed with the extremely rare cancer, pleuro pulmonary blastoma, back in 1999.
Historically, the term pulmonary blastoma has included pure fetal adenocarcinomas as well as the biphasic tumors.
If a small biopsy specimen shows only a fetal adenocarcinoma pattern, one cannot exclude the possibility of a biphasic pulmonary blastoma, realizing the blastematous component may not have been sampled.
The differential diagnostic clinical and pathologic features of pulmonary blastoma versus well-differentiated fetal adenocarcinoma and pleuropulmonary blastoma are summarized in Table 2.
Clonality and heterogeneity of pulmonary blastoma from the viewpoint of genetic alterations: a case report.
Pulmonary blastoma, carcinosarcoma and spindle-cell carcinoma: an immunohistochemical study of keratin intermediate filaments.
Dominic, who is a year and a half old, finished chemotherapy last year for pleural pulmonary blastoma and goes for checkups every three months.
2,4-11) Pulmonary blastoma is an exception in that it demonstrates an equal sex ratio and has a mean age at diagnosis of 35 years.
The 1981 World Health Organization's Histological Typing of Lung Tumours (12) recognized spindle cell carcinoma as a variant of squamous cell carcinoma; giant cell carcinoma as a variant of large cell carcinoma; and carcinosarcoma and pulmonary blastoma as miscellaneous malignant tumors.
24) In the 2004 World Health Organization classification, (1) sarcomatoid carcinomas of the lung are classified into 5 subtypes: pleomorphic carcinoma, spindle cell carcinoma, giant cell carcinoma, carcinosarcoma, and pulmonary blastoma.
2) Keratin antibodies may highlight the epithelial component of carcinosarcoma but typically diffusely stain the epithelial component of pulmonary blastoma.
The presence of malignant stroma is the primary feature distinguishing pulmonary blastoma from well-differentiated fetal adenocarcinoma.