pteroylglutamic acid

pteroylglutamic acid /pter·o·yl·glu·tam·ic ac·id/ (ter″o-il-gloo-tam´ik) folic acid.

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pter·o·yl·glu·tam·ic acid (tr-l-gl-tmk)

n.

Folic acid.

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pteroylglutamic acid.

See folic acid.

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folic acid [fo´lik]

a vitamin of the B complex; it is involved in the synthesis of amino acids and DNA. Green vegetables, liver, and yeast are major food sources; folic acid can also be produced synthetically. Folic acid deficiency (leading to megaloblastic anemia) may result from the inability of the body to use the vitamin. Because of the important role of folate in prevention of neural tube defects, it is now recommended that 400 μg of folate be taken daily before conception occurs. See also vitamin.

folic acid antagonist an antimetabolite of folic acid; some are used as antineoplastic agents because they interfere with DNA replication and cell division by inhibiting the enzyme dihydrofolate reductase. Examples include trimethoprim, an antibacterial; pyrimethamine, an antimalarial agent; and methotrexate, an antineoplastic agent.

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acid (as´id),

n a chemical substance that, in an aqueous solution, undergoes dissociation with the formation of hydrogen ions; pH levels range from 0 to 6.9. See also pH and acidic. Opposite: base.

acid, acetic,

n the acid of vinegar, sometimes used as a solvent for the removal of calculus from a removable dental prosthesis. See also solvent.

acid, ascorbic,

n See vitamin C.

acid, carbolic,

n See phenol.

acid, cevitamic,

n See vitamin C.

acid conditioning,

n the use of acid (such as phosphoric acid) to prepare the tooth surface for bonding of dental adhesives or enamel sealants.

acid etchant,

n an application of phosphoric acid used to prepare enamel surfaces to aid enamel sealant placement.

acid etching,

n the process of treating the tooth enamel, generally with phosphoric acid, by removal of approximately 40 mm of enamel rod to provide retention for enamel sealant, restorative material, or orthodontic bracket.

acid, folic,

n See vitamin B complex.

acid, hydroxypropionic

n See acid, lactic.

acid, lactic (hydroxypropionic acid),

n a monobasic acid, C₃H₆O₃, formed as an end product in the intermediary metabolism of carbohydrates. The accumulation of lactic acid in the tissues is in part responsible for the lowering of pH levels during inflammatory states; that is, the drop in pH level is believed to increase bone loss level.

acid, nicotinic,

n 1. a vitamin of the B complex group and its vitamer, niacinamide, specific for the treatment of pellagra. Niacinamide functions as a constituent of coenzyme I (DPN) and coenzyme II (TPN). Nicotinic acid is found in lean meats, liver, yeast, milk, and leafy green vegetables.
n 2. an acid (C₅H₄N [COOH]) that forms part of the B complex group of vitamins. It acts as a cofactor in intermediary carbohydrate metabolism. It is a constituent of certain coenzymes that function in oxidative-reductive metabolic systems. With niacinamide, it is a pellagra-preventive factor. Also called
niacin, P.-P. factor, pyridine 3-carboxylic acid, vitamin P.-P.

acid, orthophosphoric

n See acid, phosphoric.

acid, pantothenic

n a vitamin of the B complex group, the importance of which has not been established. It is a constituent of coenzyme A.

acid phosphatase,

n an enzyme found in the kidneys, serum, semen, and prostate gland. It is elevated in serum blood levels in individuals with prostate cancer and in individuals who have recently experienced trauma.

acid, phosphoric (HPO, orthophosphoric acid),

n the principal ingredient of silicate and zinc phosphate cement liquids.

acid, pteroylglutamic,

n See vitamin B complex.

acid salt,

n a salt containing one or more replaceable hydrogen ions.

acid, strong,

n an acid that is completely ionized in aqueous solution.

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pteroylglutamic acid

see folic acid.