psychonoxious

psy·cho·nox·ious

(sī'kō-nok'shŭs), Rarely used term for:
1. Having an unfavorable effect on the emotional life and reactions mediated by higher levels of the central nervous system; may be endogenous or exogenous.
2. Denoting people who or situations that elicit fear, pain, anxiety, or anger.
[psycho- + L. noxius, harmful]