S100A7(redirected from psoriasin 1)
S100A7A gene on chromosome 1q21 that encodes a member of the S100 family of proteins, which have 2 EF-hand calcium-binding motifs. S100 proteins are localised in the cytoplasm and/or nucleus of a wide range of cells; they are involved in regulating cell cycle progression and differentiation and other intracellular activities. The function of the S100A7-encoded protein is unknown.
S100A7 is overexpressed in the skin lesions of psoriasis, but is not a candidate gene for familial psoriasis.