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pseudopuberty

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pseudopuberty /pseu·do·pu·ber·ty/ (-pu´ber-te) development of secondary sex characters and reproductive organs that is not associated with pubertal levels of gonadotropins and gonadotropin-releasing hormone; it may be either heterosexual or isosexual.
precocious pseudopuberty  the appearance of some of the secondary sex characters without maturation of the gonads, before the normal age of onset of puberty.

pseudopuberty
[-p(y)o̅o̅′bərtē]
the appearance of somatic and functional changes in an individual before the chronologic age of puberty.

pseudopuberty
The premature development of 2º sexual characteristics, while remaining inconceivable, a phenomenon due to ↑ androgen or estrogen secretion in the face of an immature hypothalamic-adenohypophysial-gonadal axis; pseudopuberty in ♂ infants with Leydig cell tumors is associated with growth of pubic hair and penile enlargement. Cf Puberty.


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Clinical manifestations of CAH include ambiguous genitalia in girls and precocious pseudopuberty in both sexes resulting from high concentrations of adrenal androgens (simple virilizing form), with additional excessive renal sodium excretion in the salt-wasting form.
The simple virilizing form is characterized by virilization of the external genitalia in female newborns and by hypocortisolism and precocious pseudopuberty in both sexes, caused by adrenal androgen overproduction.
 
 
 
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