pseudoporphyria

pseu·do·por·phyr·i·a

(sū'dō-pōr-fir'ē-ă),
A condition clinically identical to porphyria but with no abnormality in porphyrin excretion, consequent to drug ingestion or hemodialysis.
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Differential diagnosis for the bullous stage of bullous pemphigoid * Pemphigus vulgaris * Stevens-Johnson syndrome * Pseudoporphyria * Bullous drug eruption * Dermatitis herpetiformis * Paraneoplastic pemphigus * Bullous lupus erythematosus * Porphyria cutanea tarda * Bullous impetigo * Cicatricial pemphigoid * Epidermolysis bullosa
Solar rashes such as urticaria, actinic prurigo, polymorphic light eruptions, chronic dermatitis, and pseudoporphyria.
A case of haemodialysisassociated pseudoporphyria successfully treated with oral N-acetylcysteine.
Cutaneous Reaction Patterns to Drugs Clinical Pattern Selected Drug Examples Acneiform lithium, corticosteroids, androgens Lichenoid thiazides, antimalarials, captopril Fixed drug eruption tetracyclines, sulfonamides, barbiturates Morbilliform beta-lactam antibiotics, calcium channel blockers Urticarial beta-lactam antibiotics, aspirin Pityriasis rosea-like captopril, gold Pigmentation minocycline, antimalarials, bleomycin Subacute lupus-like hydrochlorothiazide, terbinafine Systemic lupus-like procainamide, hydralazine, minocycline Serum sickness-like cefaclor, minocycline Pemphigus-like captopril, penicillamine Pseudoporphyria naproxen, furosemide Photosensitivity doxycycline, thiazides, sulfonylureas Source: Dr.
Our method provides a specific diagnosis of PCTRF and clearly differentiates it from pseudoporphyria of renal failure.
His plasma porphyrin pattern also remained unchanged, implying that pseudoporphyria is not merely a mild early version of PCTRF, but a different clinical entity.
Two of our patients with pseudoporphyria of renal failure had fecal porphyrin HPLC fractionation performed, and the results were essentially normal (data not shown).
No new adverse experiences were identified other than a single case of pseudoporphyria (a photo-induced blistering reaction), an adverse event that has been seen in patients with JRA treated with non-selective NSAIDs.