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pseudohyponatremia

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pseu·do·hy·po·na·tre·mi·a (sd-hp-n-trm-)
n.
A low serum sodium concentration resulting from volume displacement by massive hyperlipidemia or hyperproteinemia, or by hyperglycemia.

pseudohyponatremia
[-hī′pōnātrē′mē·ə]
a decreased sodium concentration that does not correspond to a true hypotonic disorder. It may result instead from volume displacement by massive hyperlipidemia or hyperproteinemia.

pseudohyponatremia [soo″do-hi″po-nah-tre´me-ah]
a decreased serum sodium concentration that does not correspond to a real hypotonic disorder, i.e., the serum osmolality is normal. It occurs when hyperlipemia increases the serum non-water volume or hyperproteinemia increases the serum non-sodium solute.

pseudohyponatremia
a condition in which marked increases in serum proteins or lipids decrease the percentage of serum water and therefore sodium.

pseudohyponatremia
Spuriously low sodium levels due to either 1. Intrinsic properties of a Pt sample–eg, hyperglycemia or hyperproteinemia–displacement of plasma water or due to the cationic nature of monoclonal proteins which bind sodium, hyperlipidemia or hyperviscosity or 2. Analytic factors, which occur when preparing samples for flame photometry or indirect potentiometry Management Both respond to vitamin 1,25–OH2D3.


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3,4) Displacement of water in a sample may lead to pseudohyponatremia when electrolytes are measured by indirect methods.
Section on Medical Management and Administration IVIG THERAPY RESULTS IN POSTINFUSIONAL HYPERVISCOSITY AND PSEUDOHYPONATREMIA ATTRIBUTABLE TO HYPERPROTEINEMIA.
 
 
 
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