pseu·do·hy·per·par·a·thy·roid·ism (s  d -h p r-p r-th roi-d zm)n. Hypercalcemia occurring in association with a malignant neoplasm but without skeletal metastases or primary hyperparathyroidism, possibly caused by the formation of parathyroid hormone by nonparathyroid tumor tissue. |
pseudohyperparathyroidism
[-hī′pərper′əthī′roidiz′əm]
signs of hypercalcemia in a cancer patent in the absence of primary hyperparathyroidism or skeletal metastases.
pseudohyperparathyroidism
persistent hypercalcemia and hypophosphatemia, due to ectopic secretion of parathyroid hormone (-like) polypeptides or other bone resorbing substances by neoplasms. Lymphosarcoma and apocrine adenocarcinoma of the anal sac in dogs are the most common source. Affected dogs show muscle weakness, anorexia, vomiting, bradycardia, polyuria and polydipsia. Nephrocalcinosis may also occur. The clinical and biochemical abnormalities are reversed if the tumor is removed. See also hyperparathyroidism.
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