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pseudohyperkalemia

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pseudohyperkalemia
[-hī′pərkəlē′mē·ə]
a laboratory artifact indicating an elevated blood potassium level caused by potassium released in vitro from cells in the blood sample.

pseudohyperkalemia
elevated levels of serum potassium resulting from an increased release from cells during clotting of the sample. Associated with thrombocytosis, extreme leukocytosis, or abnormal white or red blood cells.

pseudohyperkalemia
Lab medicine An in vitro phenomenon seen in megakaryocytic hyperplasia, thrombocytosis, leukocytosis, or myeloproliferative disease, where rapid clotting of blood releases potassium from RBCs Lab ↑ Serum K+, plasma K+ is normal. Cf Hyperkalemia.


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Pre-analytical causes Prior to running a specimen for a potassium level, there are causes that can create a factitious or pseudohyperkalemia reading, it is important to recognize these factors.
In the absence of marked leukocytosis and thrombocythemia, pseudohyperkalemia is very unlikely.
In the article, "Investigating elevated potassium values" (MLO, November 2006, page 24), little was presented to explain a case of pseudohyperkalemia that we experienced recently.
 
 
 
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