pseudobulbar palsy


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pseudobulbar palsy

paralysis of the lips and tongue, simulating progressive bulbar paralysis, but due to supranucelar lesions with bilateral involvement of the upper motor neurons; characterized by speech and swallowing difficulties, emotional instability, and spasmodic, mirthless laughter.

pseudobulbar palsy

Pseudobulbar paralysis, spastic bulbar paralysis A disease of middle age, characterized by bilateral spasticity of the facial and deglutitive muscles, resulting in dysarthria, dysphonia, dysphagia, drooling, facial weakness, hyperreflexia of extremities, and shuffling–parkinsonian gait; PP is remarkable for the variable psychiatric component, in which the Pts may have a flat affect–simulating apathy or severe depression, become enmeshed in trivialities, or have inappropriate responses to environmental cues, aka 'laughing sickness' for the characteristic pathologic–ie, inappropriate laughing–or crying Etiology Multifocal infarcts, often due to ASHD, but also to HTN, infections, trauma, degeneration Treatment Antibiotics Prognosis Guarded. Cf Bulbar palsy.

pseu·do·bul·bar pal·sy

(sū'dō-bŭl'bahr pawl'zē)
Spastic paralysis of the bulbar musculature due to bilateral impairment of corticobulbar upper motor neuron fibers.
References in periodicals archive ?
Five patients suffered hypoxic ischaemic brain injury, two had left ventricular hypertrophy, one developed pseudobulbar palsy, and the other suffered renal failure.
In severe cases, there is spastic quadriparesis and pseudobulbar palsy.
Examination showed the following striking findings: non-fatigable ophthalmoplegia and bilateral ptosis, and severe pseudobulbar palsy with a profoundly brisk jaw (and head) jerk.
Based on the presentation comprising spastic pseudobulbar palsy, ophthalmoplegia and ataxia following a period of profuse vomiting on a background of malnutrition, the patient was treated for WE with IV thiamine (100 mg 8-hourly for 7 days) and then 100 mg daily orally.
Twenty-four hours post podophyllin ingestion, the child's GCS remained 5/15; however, he had now developed abnormal neurological signs, including hypotonia, areflexia with no clonus and reduced power in all limbs, but with no evidence of a pseudobulbar palsy.
The patients were having normal ICP with no pseudomeningocele formation and pseudobulbar palsy except CSF leak, observed in 3 patients.
Most patients have a family history of this disease, and it is clinically characterized by recurrent subcortical ischemic strokes, sometimes leading to pseudobulbar palsy and dementia.
Neurologic disorders such as Arnold-Chiari malformation, myotonic dystrophy, pseudobulbar palsy, pharyngeal paresis, myasthenia gravis, and neurofibromatosis
It seems strange to cover multiple "zebras" such as pseudobulbar palsy and progressive rubella panencephalitis, and not to have a chapter on serotonin syndrome.
Motor neuron diseases include: amyotrophic lateral sclerosis (ALS, Lou Gehrig's disease), post-polio syndrome (PPS), primary lateral sclerosis (PLS), progressive muscular atrophy (PMA), pseudobulbar palsy (spastic), progressive bulbar palsy (spastic and flaccid), and spinal muscular atrophy (SMA).
Pathological laughter has been described in many clinical conditions including gelastic seizures and pseudobulbar palsy.