pseudobulbar palsy


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pseudobulbar palsy

paralysis of the lips and tongue, simulating progressive bulbar paralysis, but due to supranucelar lesions with bilateral involvement of the upper motor neurons; characterized by speech and swallowing difficulties, emotional instability, and spasmodic, mirthless laughter.

pseudobulbar palsy

Pseudobulbar paralysis, spastic bulbar paralysis A disease of middle age, characterized by bilateral spasticity of the facial and deglutitive muscles, resulting in dysarthria, dysphonia, dysphagia, drooling, facial weakness, hyperreflexia of extremities, and shuffling–parkinsonian gait; PP is remarkable for the variable psychiatric component, in which the Pts may have a flat affect–simulating apathy or severe depression, become enmeshed in trivialities, or have inappropriate responses to environmental cues, aka 'laughing sickness' for the characteristic pathologic–ie, inappropriate laughing–or crying Etiology Multifocal infarcts, often due to ASHD, but also to HTN, infections, trauma, degeneration Treatment Antibiotics Prognosis Guarded. Cf Bulbar palsy.

pseu·do·bul·bar pal·sy

(sū'dō-bŭl'bahr pawl'zē)
Spastic paralysis of the bulbar musculature due to bilateral impairment of corticobulbar upper motor neuron fibers.
References in periodicals archive ?
Most patients have a family history of this disease, and it is clinically characterized by recurrent subcortical ischemic strokes, sometimes leading to pseudobulbar palsy and dementia.
Neurologic disorders such as Arnold-Chiari malformation, myotonic dystrophy, pseudobulbar palsy, pharyngeal paresis, myasthenia gravis, and neurofibromatosis
Motor neuron diseases include: amyotrophic lateral sclerosis (ALS, Lou Gehrig's disease), post-polio syndrome (PPS), primary lateral sclerosis (PLS), progressive muscular atrophy (PMA), pseudobulbar palsy (spastic), progressive bulbar palsy (spastic and flaccid), and spinal muscular atrophy (SMA).