pseudoallergyAn adverse, nonimmunologic, anaphylaxis-like reaction of sudden onset which is associated with food ingestion; pseudoallergies may be caused by an anaphylactoid reaction, intolerance (e.g., psychogenic response), metabolic defect (e.g., enzymatic deficiency, tyramine reaction) and toxicity (e.g., tetrodotoxin).
True allergies to foods are hypersensitivity reactions caused by mast cell release of histamines evoked by IgE, which is most commonly linked to eggs, milk, peanuts, nuts, fish, soy beans and shrimp.
pseudoallergyClinical immunology A nonimmunologic, anaphylaxis-like reaction of sudden onset, associated with food ingestion; PAs may be due to an anaphylactoid reaction, intolerance–eg, psychogenic response, metabolic defect–eg, enzymatic deficiency, tyramine reaction, or toxicity–eg, tetrodotoxin. See Cheese reaction, Food allergy, Food intolerance. Cf Allergy.
pseudoallergy(sood″ō-al′ĕr-jē) [ pseudo- + allergy]
An allergic-like reaction such as an outbreak of hives that is not caused by activation of the immune system. Some instances are attributable to exposure to food colorings or preservatives.