pseudo-Bartter syndrome

pseudo-Bartter syndrome

A condition attributed to furosemide therapy, characterized by hypokalemic-hypochloremic alkalosis, hyperactivity of renin-angiotensin-aldosterone system with ↑ aldosterone, normotension, pressor inactivity of angiotensin II, ↑ urinary PGE2, ANP. Cf Bartter syndrome.
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Later development of frequent lower respiratory tract infections, pseudo-Bartter syndrome that was recognized by alkalosis associated with hypokalemia and positive F508 mutation test confirmed the diagnosis of cystic fibrosis.