Intrahepatic cholestasis of pregnancy (ICP), formerly known as pruritus gravidarum
, is due to a defect in the excretion of bile salts, causing the excess to deposit on the skin.
Intrahepatic cholestasis of pregnancy or pruritus gravidarum
(seen in 5.
Intrahepatic Cholestasis of pregnancy (ICP): (Syn: Obstetric Cholestasis, Pruritus Gravidarum, Icterus Gravidarum, Recurrent Jaundice of Pregnancy, Idiopathic Jaundice of Pregnancy)
63) ICP being referred to Pruritus Gravidarum (for pruritus without skin changes occurring early in pregnancy and related to atopic diathesis and no cholestasis) and Prurigo Gravidarum (for pruritus associated with PP like skin lesions and associated with cholestasis) lead to much confusion regarding nomenclature.
01%) each of impetigo herpetiformis, pruritus gravidarum and pemphigoid gestationis.
Of the remaining cases of pregnancy specific dermatoses, 1 case each was accounted by pruritus gravidarum, impetigo herpetiformis and pemphigoid gestationis.
Pruritus gravidarum also known as intrahepatic cholestasis of pregnancy most commonly occurs in the last trimester and is characterized by generalized pruritus, anorexia, nausea and vomiting.
1) The disorder, which is also referred to as obstetric cholestasis and pruritus gravidarum
, has no primary skin lesions.
5%) patients had pruritic urticarial papules and plaques of pregnancy (PUPP), 6 patients (3%) had pruritus gravidarum.
Chander et al Pruritus gravidarum was the most frequent dermatoses of pregnancy at 54.