prurigo nodularis


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prurigo

 [proo-ri´go]
any of several itchy skin eruptions in which the characteristic lesion is dome-shaped with a small transient vesicle on top, followed by crusting or lichenification. adj., adj prurig´inous.
prurigo gestatio´nis (prurigo gestationis of Besnier) an extremely pruritic condition of unknown etiology occurring in the third trimester of pregnancy, characterized by the development of tiny crust-covered excoriated papules mainly on the extensor surfaces of the limbs but also found on the upper trunk and other areas of the body, and leaving a postinflammatory residue on resolution of the lesions. It tends to clear after delivery and to recur with subsequent pregnancies.
prurigo mi´tis prurigo of a mild type.
prurigo nodula´ris a form of neurodermatitis, usually occurring on the extremities in middle-aged women, marked by discrete, firm, rough-surfaced, dark brownish-gray, intensely itchy nodules.
prurigo sim´plex papular urticaria.

pru·ri·go no·du·la·'ris

an eruption of hard, dome-shaped nodules (Picker nodules) in the skin caused by rubbing and accompanied by intense itching; occasionally due to mycobacterial infection, the cause is usually unknown.

lichen simplex chronicus

A dermopathy characterised by intensely pruritic nodules on the arms or legs, often with excoriations due to itching.

Aetiology
Idiopathic; it may be associated with Becker's nevus, linear IgA disease, and liver disease, and triggered by internal malignancy, liver or renal failure.

DiffDx
Systemic pruritus—cholestasis, thyroid disease, polycythaemia rubra vera, uraemia, Hodgkin lymphoma, HIV and other immune deficiencies; delusions of parasitosis and other psychiatric conditions.

pru·ri·go no·du·la·ris

(prū-rī'gō nod'yū-lār'is)
An eruption of hard nodules (picker's nodules) in the skin caused by rubbing and accompanied by intense itching.

Hyde,

James N., U.S. dermatologist, 1840-1910.
Hyde disease - an eruption of hard nodules in the skin caused by rubbing and accompanied by intense itching. Synonym(s): picker's nodules; prurigo nodularis
References in periodicals archive ?
Lesions like leprosy, erythema nodosum leprosum, trichoepithelioma, Metastatic carcinoma were more common in males, while Prurigo Nodularis and granuloma annulare were more common in females.
Combination therapy of fexofenadine and montelukast is effective in prurigo nodularis and pemphigoid nodularis.
In cea de a doua categorie se gasesc afectiuni dermatologice cronice, precum psoriazisul, acneea excoriatica, alopecia, dermatita atopica, formele cronice de urticarie, eczema endogena, prurigo nodularis, boala Darier, lichen simplex chronicus, infectiile herpetice recidivante etc.
Prodromal veya erken evre BP ilk olarak 1985 yilinda Asbrink ve Hovmark (46) tarafindan tanimlanmis olup, bul veya vezikul olmaksizin yaygin pruritus, yaygin urtikeryal plaklar, eritemli plaklar, prurigo nodularis tipi lezyonlar veya eritrodermi ile seyreden olgular bildirilmistir.
Berger's patients on thalidomide for prurigo nodularis developed stroke.
7 Prurigo nodularis, vitiligo, melasma, hyperkeratosis and fissures on the soles, papular urticaria, chronic dermatitis of leg, seborrheic dermatitis of the scalp, varicose eczema and Schamberg's disease are reported but their association with CRF cannot be assured definitely.
Patients with prurigo nodularis experience intractable itching and consequent breakdown and secondary infection of the affected skin.
Psychiatric diseases have a lot of cutaneous expression, like in neurodermatoses such as lichen simplex chronicus, prurigo nodularis, dermatitis artefacta, delusional parasitosis and psychogenic pruritus.
Atopik dermatit, kontakt dermatit, impetigo, bocek isirmasi, norodermit, follikulit, prurigo nodularis, pemfigoid ve pemfigus gibi bulloz deri lezyonlari, psoriazis ve diger pek cok dermatoz ile karisabilen lezyonlar olusturabilir (8,9).
My hypothesis is that prurigo nodularis is a keloid of the nerve," he said, induced in predisposed patients by rubbing and scratching.
Especially effective in prurigo nodularis, this drug can be used for itch at dosages of 50-200 mg daily.
pyoderma gangrenosum, polyarteritis nodosa, vasculitis, sarcoidosis, Sweet's syndrome, and prurigo nodularis.