In September 2012, a 21-year-old man was admitted to the emergency department of our hospital with complaints of high fever, cough, sore throat, chest pain, polyarthralgia and polyarthritis involving the wrists, knees, ankles, and proximal interphalangeal joints
, and progressive weight loss of 6 kg in 2 months.
2], and her proximal interphalangeal joints
were mildly warm and tender bilaterally (Figure 2).
Efficacy and Safety of Collagenase Clostridium Histolyticum (CCH) in the Treatment of Proximal Interphalangeal Joints
in Dupuytren Contracture: Combined Analysis of Four Phase 3 Clinical Trials (Clinical Paper 80, Clinical Paper Session 18: Dupuytren's Disease, Saturday, October 5, 4:10 - 4:16 p.
The inflammation waxes and wanes over the course of years, resulting in knobbly, painful, inflamed knuckles and finger deformities of the distal and proximal interphalangeal joints
Wrist involvement occurs most often (70-90%), but RA can also be found in the metacarpophalangeal joints (MCPJs) and proximal interphalangeal joints
At 30 days, 60% of all joints, 76% of metacarpophalangeal (MP) and 33% proximal interphalangeal joints
achieved clinical success (defined as joint correction to 0 to 5 degrees) following this single injection when two 0.
In this position, the distal interphalangeal joints are extended, the proximal interphalangeal joints
are flexed, and the metacarpal joints are extended.
Her hands exhibit Heberden's and Bouchard"s nodes on distal and proximal interphalangeal joints
History and physical examination revealed intense pain, allodynia, hyperpathia, hyperemia, contracture of the wrist, of the metacarpophalangeal joints and of the proximal interphalangeal joints
, abnormal sweating, and increased hair growth over the dorsum of the hand, hypoesthesia, dystrophic nail changes and tremor in the right hand.
Small joints" were the metacarpophalangeal joints, proximal interphalangeal joints
, second through fifth metatarsophalangeal joints, thumb interphalangeal joints, and wrists.
Involvement of 1-3 "small" joints (defined as metacarpophalangeal joints, proximal interphalangeal joints
, second to fifth metatarsophalangeal joints, thumb interphalangeal joints, and wrists) gets 2 points, regardless of large-joint involvement; involvement of 4-10 small joints gets 3 points.
86% of metacarpophalangeal joints, MCP joints (12 of 14), and 100% of proximal interphalangeal joints
, PIP joints (9 of 9), were successfully treated.