challenge

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challenge

 [chal´enj]
1. to administer a chemical substance to a patient for observation of whether the normal physiological response occurs.
2. in immunology, to administer antigen to evoke an immunologic response in a previously sensitized individual.
3. the administration of such a substance in order to assess for a response; called also provocation.
bronchial challenge (inhalational challenge) bronchial challenge test.

challenge

/chal·lenge/ (chal´enj)
1. to administer a substance to monitor for the normal physiological response.
2. in immunology, to administer an antigen to monitor the response in a sensitized person.

challenge

(chăl′ənj)
n.
Immunology The induction or evaluation of an immune response in an organism by administration of a specific antigen to which it has been sensitized.
v. chal·lenged, chal·lenging, chal·lenges
v.tr.
Immunology To induce or evaluate an immune response in (an organism) by administering a specific antigen to which it has been sensitized.

chal′lenge·a·ble adj.

challenge

1 a method of testing the sensitivity of an individual to a hormone, allergen, or other substance by administering a sample. A small amount may be injected to determine whether the immune system will react by producing appropriate antibodies.
2 a term used to describe the rapid or concentrated infusion of a substance such as potassium or magnesium in the face of a life-threatening deficiency or a rapid infusion of IV fluid to differentiate between fluid deficit or renal failure as the cause of severely decreased urine output.

challenge

Immunology The administration of an antigen or allergen to a person who has been previously exposed to the antigen, specifically to evoke an immune response

challenge,

n a stimulating or de-manding circumstance. To develop effective problem-solving skills and strategies, it is necessary to perceive such circumstance as inconvenience or burden instead of overwhelming impediments.
References in periodicals archive ?
SEUL (CyHAN)- SEOUL -- South Korea's top military officer on Friday warned the Democratic People's Republic of Korea (DPRK) of "a harsh price" for any further provocations.
Turkey's decision to unilaterally issue a Notice to Airmen ("NOTAM"), reserving an extensive airspace over the Aegean Sea from the 2 nd of March to 31 st of December for military use is considered a serious provocation, with the Greek government prepared to take the matter to NATO, the United Nations, the European Union and the International Civil Aviation Authority (ICAO).
has distinct provocation a much younger, bigge" There has been a distinct provocation from a much younger, much bigger woman.
Researchers found however that this aggressive behaviour occurred when people were subjected to provocation in a way that was not a clear-cut insult.
According to him, the cause of the conflict which previously occurred in Batken region is not a provocation.
The visit came amid rising fears that North Korea could resort to provocation anytime to divert the country's collective attention away from the monstrous execution of leader Kim's once-powerful uncle Chang Song-thaek (aka Jang Song-thaek).
A provocation triggered the US war in Vietnam and NATO's bombardments of Serbia.
Future Movement called on all Lebanese students to be aware of the seriousness of being dragged into any provocation, urging them to preserve their universities as a strong setting for democracy and respect for the opinions of others.
Faced with escalating provocation from Pyongyang, Washington is stepping up pressure on the country by sending B-52 strategic bombers to join U.
Summary: Seoul: South Korean President Park Geun-Hye vowed "strong retaliation" Monday to any provocation by North .
Secretary of Defense Chuck Hagel vowed Thursday in a phone conversation to make a "strong response" to any North Korean military provocation, South Korea's defense ministry spokesman told a news briefing.
Warren Faulkener, 41, of Webb Avenue, Seaham, has been charged with fear/ provocation of violence and possessing a controlled drug, and an 18-year-old male has been given a caution for fear/ provocation of violence.