provirus


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provirus

 [pro-vi´rus]
a DNA transcript of an RNA virus that migrates from the cytoplasm into the nucleus and integrates into the host genome by crossing over so that it will be thus replicated in the daughter cells.

pro·vi·rus

(prō-vī'rŭs),
The precursor of an animal virus, usually a retrovirus; theoretically analogous to the prophage in bacteria, the provirus is integrated in the nucleus of infected cells and can be activated in response to certain stimuli.

provirus

/pro·vi·rus/ (pro-vi´rus) the genome of an animal virus integrated (by crossing over) into the chromosome of the host cell, and thus replicated in all of its daughter cells. It can be activated to produce a complete virus; it can also cause transformation of the host cell.

provirus

(prō′vī′rəs, prō-vī′-)
n. pl. provi·ruses
A form of a virus that allows it to be integrated into the genome of a host cell and to replicate in concert with the cell's genetic material without causing cell lysis.

pro′vi′ral (-rəl) adj.

provirus

[-vī′rəs]
a stage of viral replication in which the viral genetic information has been integrated into the genome of the host cell. It may be activated spontaneously or by a specific stimulus to direct the cell to produce new virions to progress to a complete virus.

pro·vi·rus

(prō-vī'rŭs)
The precursor of an animal virus; theoretically analogous to the prophage in bacteria, the provirus being integrated into the nucleus of infected cells.

provirus

the DNA of a VIRUS that has integrated into the DNA of the host CELL and is transmitted from one cell generation to the next in this state. No infective virus particles are produced. The provirus can excise from the host's DNA and resume a productive viral cycle with the production of virus particles.

pro·vi·rus

(prō-vī'rŭs)
The precursor of an animal virus; theoretically analogous to the prophage in bacteria, the provirus being integrated into the nucleus of infected cells.

provirus (prōvī´rus),

n a type of virus incorporated into a host cell's genetic material that transmits from one generation of cells to the next via cell replication without triggering the separation or decomposition of the cell.

provirus

the genome of an animal virus integrated into the chromosome of the host cell, and thus transferred to in all of its daughter cells.
References in periodicals archive ?
Los metodos experimentales usados para la extraccion de las secuencias adyacentes al provirus debian ser IPCR o LMPCR.
Provirus load in breast milk and risk of mother-to-child transmission of human T lymphotropic virus type I.
Integracion del provirus en las proximidades de un c-onc: retrovirus de transformacion lenta o cis-activantes, o transformantes debiles: virus de leucemias.
We know that provirus does not make virus until the cell containing it is 'activated'.
The provirus can remain latent in the host cell's genome for months to years (Wilson, 1997).
Cuando estas celulas se activan para responder a la presencia de agentes infecciosos, el provirus se despierta --dice Gee--, empieza a producir mas virus y destruye a las celulas desde adentro.
Discrete regions of sequence homology between cloned rodent VL30 genetic elements and AKV-related MuLV provirus genome.
Host factors that affect provirus stability and silencing
Actua editando secuencias de RNA y DNA extranos, deaminando citosina (C) a uracilo (U): este cambio conduce a que durante la escision por reparacion de bases se presenten cambios de G por A, acumulando multiples codones de parada y generando un bloqueo especifico en la transcripcion inversa; de esta manera se suprime la sintesis de la cadena positiva de cDNA y se induce su degradacion por endonucleasas antes de la integracion del provirus.
Similarly, these authors observed a tendency for increased provirus load in cattle with G/G homozygote compared to A/A homozygote or A/G heterozygote.
Knockdown of all members of the PAF1 family of proteins enhanced HIV-1 reverse transcription and integration of provirus.