protriptyline hydrochloride

0.01 sec.

[-trip′tilēn]

a tricyclic antidepressant.

indications It is prescribed in the treatment of endogenous depression marked by withdrawal and anergy.

contraindications Concomitant administration of monoamine oxidase inhibitors, recent myocardial infarction, or known hypersensitivity to any tricyclic medication prohibits its use. It is used with caution when anticholinergics are contraindicated, in seizure disorders, and in cardiovascular disease.

adverse effects Among the more serious adverse effects are sedation and anticholinergic side effects. A variety of GI, cardiovascular, and neurologic reactions may occur. It interacts with many other drugs.

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